Bacteraemia due to Eikenella corrodens secondary to periodontal infection in a neutropenic patient
Keywords:
Eikenella corrodens. Bacteriemia. Agranulocitosis. Carbimazol.Abstract
We present the case of a 44year-old patient, without significant previous medical history, who presented a systemic infection due to Eikenella corrodens following a dental extraction in the context of an agranulocitosis of pharmacological origin due to carbimazole. During admission he was treated with broad-spectrum antibiotics and G-CSF 5 μg/kg/day, undergoing a favorable evolution and receiving hospital discharge on the seventh day. Invasive infections due to Eikenella corrodens that develop bacteriaemia are less than 20%, and are generally secondary to the drainage of previous abscesses and are usually isolated together with other microorganisms; while finding a monomicrobial primary bacteriaemia without the prior existence of endocarditis is exceptional. This is the first case of systemic infection due to this bacteria secondary to dental manipulation, where the state of transitory immunosuppression in which the patient found himself at that time was determinant in causing the disseminated infection.Downloads
References
. JARAMILLO RD, SUÁREZ P, BARRAZA B, LARA P, TEHERÁN L, ESCAMILLA JE. Eikenella corrodens: patogénesis y aspectos clínicos. Colomb Med 2006; 37: 228-241.
https://doi.org/10.25100/cm.v37i3.450
2. CERCENADO E, CERCENADO S, BOUZA E. In vitro activies of Tigecycline (GAR-936) and 12 other antimicrobial agents against 90 Eikenella corrodens clinical isolates. Antimicrobial Agents and Chemotherapy 2003; 47: 2644-2645.
https://doi.org/10.1128/AAC.47.8.2644-2645.2003
3. GASSER I, MORENO G, FERRER A, CAPDEVILA JA, VALME I. Eikenella corrodens: five year experience in a general hospital. Enferm Infecc Microbiol Clin 1999; 17: 394-397.
4. FUJISE O, CHEN W, RICH S, CHEN C. Clonal diversity and stability of subgingival Eikenella corrodens. J Clin Microbiol 2004; 42: 2036-2042.
https://doi.org/10.1128/JCM.42.5.2036-2042.2004
5. UDAKA T, HIRAKI N, SHIOMORI T, MIYAMOTO H, FUJIMURA T, INABA T et al. Eikenellla corrodens in head and neck infections. J Infect 2007; 54: 343-348.
https://doi.org/10.1016/j.jinf.2005.06.015
6. NEWFIELD RS, VARGAS I, HUMA Z. Eikenella corrodens. Case report in two adolescent females with IDDM. Diabetes Care 1996; 19: 1011-1013.
https://doi.org/10.2337/diacare.19.9.1011
7. PIT S, JAMAL F, CHEAH FK. Microbiology of cerebral abscess: a four-year study in Malaysia. J Trop Med Hyg 1993; 96: 191-196.
8. ROSEN T. Penile ulcer from traumatic orogenital contact. Dermatol Online J 2005; 11: 18.
https://doi.org/10.5070/D35M33937N
9. ÖZTOPRAK N, BAYAR Ü, CELEBRI G, BASARAN M, CÖMERT F. Eikenella corrodens, cause of a vulvar abscess in a diabetic adult. Infect Dis Obstet Gynecol 2007; 17: 63565.
https://doi.org/10.1155/2007/63565
10. HEIRO M, NIKOSKELAINEN J, ENGBLOM E, KOTILAINEN P. Eikenella corrodens prosthetic valve endocarditis in a patient with ulcerative colitis. Scand J Infect Dis 2000; 32: 324-325.
https://doi.org/10.1080/00365540050166027
11. LORENZO-GARDE L, BOLAÑOS-RIVERO M, TURÉGANO-GARCÍA A, MARTÍN-SÁNCHEZ AM. Abscesos intraperitoneales por Eikenella corrodens. Rev Esp Quimioter 2011; 24: 115-116.
12. SHENG WS, HSUEH PR, HUNG CC, TENG LJ, CHEN YC, LUH KT. Clinical features of patients with invasive Eikenella corrodens infections and microbiological characteristics of the causative isolates. Eur J Clin Microbiol Infect Dis 2001; 20: 231-236.
https://doi.org/10.1007/PL00011259
13. ZGHEIB A, EL ALLAF D, DEMONTY J, ROVIVE G. Intrathoracic infections with bacteraemia due to Eikenella corrodens as a complication of peritonsilar abscesses: report of a case and review of the literature. Acta Clin Belg 1992; 47: 124-128.
https://doi.org/10.1080/17843286.1992.11718218
14. MÖKEMÜLLER KE, BRONZE MS. Immunoblastic lymphadenopathy presenting as an acute abdomen and mixed bacteremia with Eikenella corrodens and group C streptococci. Am J Gastroenterol 1998; 93: 652-653.
https://doi.org/10.1111/j.1572-0241.1998.186_b.x
15. CENDEJAS-BUENO E, ROMERO-GÓMEZ MP, SÁEZ-NIETO JA, OMEÑACA-TERÉS F, ARES-SEGURA S, PEÑA-GARCÍA P. Sepsis neonatal por Eikenella corrodens. An Pediatr (Barc) 2007; 67: 603-614.
https://doi.org/10.1016/S1695-4033(07)70811-1
16. CASTILLO DM, SÁNCHEZ-BELTRÁN MC, CASTELLANOS JE, SANZ I, MAYORGA-FAYAD I, SANZ M et al. Detection of specific periodontal microorganisms from bacteraemia samples after periodontal therapy using molecular-based diagnostics. J Clin Periodontol 2011; 38: 418-427.
Published
How to Cite
Issue
Section
License
Copyright (c) 2012 Anales del Sistema Sanitario de Navarra
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
La revista Anales del Sistema Sanitario de Navarra es publicada por el Departamento de Salud del Gobierno de Navarra (España), quien conserva los derechos patrimoniales (copyright ) sobre el artículo publicado y favorece y permite la difusión del mismo bajo licencia Creative Commons Reconocimiento-CompartirIgual 4.0 Internacional (CC BY-SA 4.0). Esta licencia permite copiar, usar, difundir, transmitir y exponer públicamente el artículo, siempre que siempre que se cite la autoría y la publicación inicial en Anales del Sistema Sanitario de Navarra, y se distinga la existencia de esta licencia de uso.
