Lesiones esofágicas agudas inducidas por drogas y uso de ciprofloxacino

Authors

  • V. Modesto dos Santos Catholic University and Armed Forces Hospital
  • M. Vasconcelos Carneiro Armed Forces Hospital
  • L. Rodrigues da Cruz Armed Forces Hospital
  • G. Teixeira Guimarães Paixão Armed Forces Hospital

Keywords:

Aged. Ciprofloxacin. Drug-induced esophagitis. Endoscopy.

Abstract

Presentamos el caso de una mujer de 95 años con lesiones agudas del esófago que tomaba ciprofloxacino por cistitis aguda. La paciente refería dolor y sensación de cuerpo estraño retroesternal asociados con hematemesis y melena, después del segundo día de tratamiento. No había antecedentes personales de trastornos gástricos o esofágicos. La endoscopia digestiva objetivó lesiones sangrantes en el tercio medio del esófago. El uso de ciprofloxacino fue suspendido y se utilizó un inhibidor de la bomba de protones. Una semana más tarde, el aspecto endoscópico del esófago fue considerado normal. Dos únicos casos de lesiones esofágicas inducidas por ciprofloxacino han sido previamente publicados. Se presenta una revisión breve acerca de este tipo de lesiones del esófago, con énfasis a los principales factores de riesgo y medidas de prevención.

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References

1. ABID S, MUMTAZ K, JAFRI W, HAMID S, ABBAS Z, SHAH HA et al. Pill-induced esophageal injury: endoscopic features and clinical outcomes. Endoscopy 2005; 37: 740-744.

https://doi.org/10.1055/s-2005-870129

2. AKHTAR AJ. Oral medication-induced esophageal injury in elderly patients. Am J Med Sci 2003; 326: 133-135.

https://doi.org/10.1097/00000441-200309000-00005

3. ARORA AS, MURRAY JA. Iatrogenic esophagitis. Curr Gastroenterol Rep 2000; 2: 224-229.

https://doi.org/10.1007/s11894-000-0065-1

4. No authors listed. [Drug-induced esophageal injuries-an overview. Adverse effects of felodipine and ciprofloxacin observed during 2 years]. Lakartidningen 1990; 87: 2368-2369.

5. EMAMI MH, HAGHIGHI M, ESMAEILI A. Esophagitis caused by ciprofloxacin: a case report and review of the literature. Govaresh 2004; 9: 272-276.

6. NARANJO CA, BUSTO U, SELLERS EM, SANDOR P, RUIZ I, ROBERTS EA et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30: 239-245.

https://doi.org/10.1038/clpt.1981.154

7. PEMBERTON J. Oesophageal obstruction and ulceration caused by oral potassium therapy. Br Heart J 1970; 32: 267-268.

https://doi.org/10.1136/hrt.32.2.267

8. KIKENDALL JW. Pill esophagitis. J Clin Gastroenterol 1999; 28: 298-305.

https://doi.org/10.1097/00004836-199906000-00004

9. LEONG RW, CHAN FK. Drug-induced side effects affecting the gastrointestinal tract. Expert Opin Drug Saf 2006; 5: 585-592.

https://doi.org/10.1517/14740338.5.4.585

10. ZOGRAFOS GN, GEORGIADOU D, THOMAS D, KALTSAS G, DIGALAKIS M. Drug-induced esophagitis. Dis Esophagus 2009; 22: 633-637.

https://doi.org/10.1111/j.1442-2050.2009.00972.x

11. O'NEILL JL, REMINGTON TL. Drug-induced esophageal injuries and dysphagia. Ann Pharmacother 2003; 37: 1675-1684.

https://doi.org/10.1345/aph.1D056

12. JASPERSEN D. Drug-induced oesophageal disorders: pathogenesis, incidence, prevention and management. Drug Saf 2000; 22: 237-249.

https://doi.org/10.2165/00002018-200022030-00007

13. KIKENDALL JW. Pill-induced esophageal injury. Gastroenterol Clin North Am 1991; 20: 835-846.

https://doi.org/10.1016/S0889-8553(21)00591-4

14. SANTOS VM, VILLAÇA RB, GOUVÊA LP, SÁ DAR. Comment on the clinical note: Acute necrotizing esophagitis in an unstable patient. An Sist Sanit Navar 2009; 32: 439-442.

https://doi.org/10.4321/S1137-66272009000500013

15. STAHLMANN R, LODE H. Safety considerations of fluoroquinolones in the elderly: an update. Drugs Aging 2010; 27: 193-209.

https://doi.org/10.2165/11531490-000000000-00000

16. ESCRIBANO E, CALPENA AC, GARRIGUES TM, FREIXAS J, DOMENECH J, MORENO J. Structure-absorption relationships of a series of 6-fluoroquinolones. Antimicrob Agents Chemother 1997; 41: 1 996-2000. Erratum in: Antimicrob Agents Chemother 1997; 41: 2595.

https://doi.org/10.1128/AAC.41.9.1996

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Published

2012-05-02

How to Cite

1.
Modesto dos Santos V, Vasconcelos Carneiro M, Rodrigues da Cruz L, Teixeira Guimarães Paixão G. Lesiones esofágicas agudas inducidas por drogas y uso de ciprofloxacino. An Sist Sanit Navar [Internet]. 2012 May 2 [cited 2026 Jan. 31];35(1):127-31. Available from: https://recyt.fecyt.es/index.php/ASSN/article/view/14152

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Section

Clinical notes

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