A case report of severe hypocalcemia secondary to Fahr’s syndrome
DOI:
https://doi.org/10.23938/ASSN.1138Keywords:
Hypocalcemia, Hypoparathyroidism, Brain calcifications, Rare Diseases, Fahr´s SyndromeAbstract
Fahr's syndrome is a rare neurological disease characterized by bilateral intracranial calcifications associated with disturbances in calcium-phosphate metabolism, most commonly due to hypoparathyroidism.
We report a 56-year-old man presenting with generalized seizures and behavioral changes. Laboratory evaluation revealed severe hypocalcemia, hyperphosphatemia, and low parathyroid hormone levels. Brain computed tomography demonstrated symmetrical calcifications involving the basal ganglia and other subcortical structures, consistent with Fahr's syndrome. Diagnosis was established through the integration of clinical features, biochemical abnormalities, and neurological findings, after excluding alternative causes of intracranial calcifications, including infectious, autoimmune, and genetic conditions. Management focused on prompt correction of hypocalcemia and long-term metabolic control with close biochemical monitoring.
Early recognition of hypoparathyroidism is essential to prevent neurological complications and improve outcomes. This case highlights the pivotal role of laboratory assessment in the diagnosis and management of Fahr´s syndrome.
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