Extrato roxo de batata doce e exercício aeróbico reduzem perfis lipídicos em modelo de rato hiperlipidêmico
DOI:
https://doi.org/10.47197/retos.v55.99966Palavras-chave:
Aerobic exercise, hyperlipidemia, lipid profile, purple sweet potatoResumo
A obesidade e a dislipidemia são os principais fatores de risco para doenças cardiovasculares. Foi demonstrado que a suplementação dietética combinada com exercícios de intensidade adequada melhora o perfil lipídico e reduz o risco de doenças cardiovasculares. Este estudo investiga o efeito do extrato de batata doce roxa e do treinamento de natação no perfil lipídico de um modelo de rato hiperlipidêmico. Vinte e cinco ratos Wistar machos foram agrupados com dieta padrão e dieta rica em gordura e alimentados com suas respectivas dietas por duas semanas. Em seguida, foram divididos aleatoriamente em cinco grupos de mesmo peso; controle normal (C; n=5), dieta rica em gordura (HF; n=5), exercício (E; n=5), extrato de batata doce roxa (PSP; n=5) e exercício combinado com extrato de batata doce roxa (EPSP; n=5). Extrato de batata-doce roxa 100 mg/dia foi administrado por gavagem oral durante três semanas. O exercício de natação foi realizado durante 30 minutos por dia, cinco dias por semana, durante três semanas, na intensidade de 6% do peso corporal. Ao final do período experimental, foram coletadas amostras de sangue intracardíaco para mensuração do perfil lipídico. Técnica de análise de dados utilizando teste ANOVA unidirecional com nível de significância de 5%. Os achados revelaram que a concentração de CT e LDL foi maior na IC. A combinação de exercício e extrato de batata doce roxa reduziu significativamente o LDL e aumentou os níveis de HDL em comparação ao exercício ou PSP isoladamente (p ≤ 0,05). Indica que o extrato de batata doce roxa combinado com exercícios de natação demonstrou ser eficaz na melhoria do perfil lipídico em modelos de ratos hiperlipidêmicos.
Palavras-chave: Exercício aeróbico, hiperlipidemia, perfil lipídico, batata doce roxa.
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