Rhodiola Rosea: a plant from the Crassulaceae family that has the potential to reduce muscle pain and increase range of motion during exercise-induced muscle damage

Authors

DOI:

https://doi.org/10.47197/retos.v58.107977

Keywords:

Rhodiola Rosea, Muscle Pain, Range of Motion, Exercise-Induced Muscle Damage, Inflammation

Abstract

This study aims to analyze the potential of rhodiola rosea in reducing muscle pain and increasing ROM during EIMD. This experimental research uses a pre- and post-control group design. Research subjects were selected using a purposive sampling technique, then the subjects were divided into 2 groups, namely group (K1) which was given placebo and group (K2) which was given rhodiola rosea at a dose of 500 mg. A total of 18 healthy men aged between 19-25 years participated in this study. Data collection began on the first day by collecting data on subject characteristics. After that, they were asked to warm up. Physical activity is carried out afterward. These activities include high-intensity activities, such as walking lunges, good mornings, and leg extensions. This exercise is done in 4 sets with a 1-minute break (recovery) between sets. Exercise intensity is monitored using a Polar H9 Heart Rate Sensor. On day 2 or 24 hours after training, subjects took pre-test data to measure muscle soreness and ROM. Subjects were then given placebo or rhodiola rosea treatment, depending on the group assigned. On the 3rd day or 48 hours after training, post-test data was collected again. Muscle intensity was measured using a Visual Analog Scale (VAS) and ROM was measured at the knee joint using a goniometer. After the data was obtained, the data were analyzed using the IBM SPSS version 26 application. The results of this study reported that the K1 group given placebo did not significantly reduce muscle pain and increase ROM during EIMD, while the K2 group given rhodiola rosea at a dose of 500 mg significantly reduced pain. muscle and increase ROM during EIMD. Considering that pain management and ROM are very necessary to support body function, we recommend the use of rhodiola rosea for sports enthusiasts to support physical performance.

Keywords: Rhodiola Rosea, Muscle Pain, Range of Motion, Exercise-Induced Muscle Damage, Inflammation, Healthy lifestyle

References

Ayubi, N., Yuniarti, E., Kusnanik, NW., Herawati, L., Indika, PM., Putra RY., Komaini, A. (2022). Acute effects of n-3 polyunsaturated fatty acids (PUFAs) reducing tumor necrosis factor-alpha (TNF-a) levels and not lowering malondialdehyde (MDA) levels after anaerobic exercise. Journal of Biological Regulators and Homeostatic Agents, 36(1); 7-11 https://doi.org/10.23812/21-468-A.

Ayubi, N., Purwanto, B., Rejeki, PS., Kusnanik, NW., Herawati, L., Komaini, A., Mutohir, TC., Nurhasan, N., Al Ardha, MA., & Firmansyah, A. (2022). Effect of acute omega 3 supplementation reduces serum tumor necrosis factor-alpha (TNF-a) levels, pain intensity, and maintains muscle strength after high-intensity weight training. Retos, 46; 677–682. https://doi.org/10.47197/retos.v46.93720.

Bernatoniene, J., Jakstas, V., Kopustinskiene, DM. (2023). Phenolic Compounds of Rhodiola rosea L. as the Potential Alternative Therapy in the Treatment of Chronic Diseases. International Journal of Molecular Sciences, 24(15); 12293. https://doi.org/10.3390/ijms241512293.

Drafi, F., Bauerova, K., Chrastina, M., Taghdisiesfejír, M., Rocha, J., Direito, R., Figueira, ME., Sepodes, B., Ponist, S. (2023). Rhodiola rosea L. Extract, a Known Adaptogen, Evaluated in Experimental Arthritis. Molecules, 28(13); 5053. https://doi.org/10.3390/molecules28135053.

Ezike, TC., Okpala, US., Onoja, UL., Nwike, CP., Ezeako, EC., Okpara, OJ., Okoroafor, CC., Eze, SC., Kalu, OL., Odoh, EC., Nwadike, UG., Ogbodo, JO., Umeh, BU., Ossai, EC., & Nwanguma, BC. (2023). Advances in drug delivery systems, challenges and future directions. Heliyon, 9(6); e17488. https://doi.org/10.1016/j.heliyon.2023.e17488.

Fernández-Lázaro, D., Mielgo-Ayuso, J., Seco Calvo, J., Córdova Martínez, A., Caballero García, A., & Fernandez-Lazaro, C. I. (2020). Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review. Nutrients, 12(2); 501. https://doi.org/10.3390/nu12020501.

Hody, S., Croisier, JL., Bury, T., Rogister, B., & Leprince, P. (2019). Eccentric Muscle Contractions: Risks and Benefits. Frontiers in physiology, 10; 536. https://doi.org/10.3389/fphys.2019.00536.

Ivanova Stojcheva, E., & Quintela, J. C. (2022). The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence. Molecules (Basel, Switzerland), 27(12); 3902. https://doi.org/10.3390/molecules27123902.

Konrad, A., Kasahara, K., Yoshida, R., Yahata, K., Sato, S., Murakami, Y., Aizawa, K., & Nakamura, M. (2022). Relationship between Eccentric-Exercise-Induced Loss in Muscle Function to Muscle Soreness and Tissue Hardness. Healthcare (Basel, Switzerland), 10(1); 96. https://doi.org/10.3390/healthcare10010096.

Lee, Y., Jung, JC., Jang, S., Kim, J., Ali, Z., Khan, IA., & Oh, S. (2013). Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea. Evidence-based complementary and alternative medicine : eCAM, 2013; 514049. https://doi.org/10.1155/2013/514049.

Li, Y., Pham, V., Bui, M., Song, L., Wu, C., Walia, A., Uchio, E., Smith-Liu, F., & Zi, X. (2017). Rhodiola rosea L.: an herb with anti-stress, anti-aging, and immunostimulating properties for cancer chemoprevention. Current pharmacology reports, 3(6); 384–395. https://doi.org/10.1007/s40495-017-0106-1.

Lu, Y., Deng, B., Xu, L., Liu, H., Song, Y., & Lin, F. (2022). Effects of Rhodiola Rosea Supplementation on Exercise and Sport: A Systematic Review. Frontiers in nutrition, 9; 856287. https://doi.org/10.3389/fnut.2022.856287.

Mahesh, G., Anil Kumar, K., & Reddanna, P. (2021). Overview on the Discovery and Development of Anti-Inflammatory Drugs: Should the Focus Be on Synthesis or Degradation of PGE2?. Journal of inflammation research, 14; 253–263. https://doi.org/10.2147/JIR.S2785144.

Nanavati, K., Rutherfurd-Markwick, K., Lee, SJ., Bishop, NC., & Ali, A. (2022). Effect of curcumin supplementation on exercise-induced muscle damage: a narrative review. European journal of nutrition, 61(8); 3835–3855. https://doi.org/10.1007/s00394-022-02943-7.

Nonnenmacher, Y., & Hiller, K. (2018). Biochemistry of proinflammatory macrophage activation. Cellular and molecular life sciences : CMLS, 75(12); 2093–2109. https://doi.org/10.1007/s00018-018-2784-1.

Paulsen, G., Crameri, R., Benestad, HB., Fjeld, JG., Mørkrid, L., Hallén, J., & Raastad, T. (2010). Time course of leukocyte accumulation in human muscle after eccentric exercise. Medicine and science in sports and exercise, 42(1); 75–85. https://doi.org/10.1249/MSS.0b013e3181ac7adb.

Tsagareli, M. G., Tsiklauri, N., Nozadze, I., & Gurtskaia, G. (2012). Tolerance effects of non-steroidal anti-inflammatory drugs microinjected into central amygdala, periaqueductal grey, and nucleus raphe: Possible cellular mechanism. Neural regeneration research, 7(13); 1029–1039. https://doi.org/10.3969/j.issn.1673-5374.2012.13.010.

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Published

2024-07-29

How to Cite

Ayubi, N., Komaini, A., Aljunaid, M. ., Jr., P. B. D., Ilham, I., & Mario, D. T. (2024). Rhodiola Rosea: a plant from the Crassulaceae family that has the potential to reduce muscle pain and increase range of motion during exercise-induced muscle damage. Retos, 58, 1112–1116. https://doi.org/10.47197/retos.v58.107977

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Original Research Article

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