Efectos del entrenamiento de resistencia de alta intensidad sobre el cortisol salival en individuos entrenados: una revisión sistemática (Effects of high-intense resistance training on salivary cortisol in trained individuals: a systematic review)




Palabras clave:

Entrenamiento de resistencia, Saliva, Cortisol


Este estudio tuvo como objetivo evaluar los efectos del entrenamiento de alta intensidad sobre los niveles de cortisol salival en individuos entrenados físicamente. Esta revisión sistemática siguió las recomendaciones de PRISMA. La búsqueda de artículos científicos se realizó en las bases Scopus y MEDLINE (vía PubMed) con los términos entrenamiento de resistencia, saliva, cortisol y sus sinónimos. Se incluyeron intervenciones con entrenamiento de resistencia de alta intensidad que analizaron los niveles de cortisol salival en hombres y mujeres entrenados físicamente. De los 399 artículos encontrados, ocho estudios cumplieron los criterios de inclusión. Una población de 135 hombres entrenados físicamente y 12 mujeres tiene una edad de 23,26±3,10 años, masa corporal de 85,53±12,68 kg y altura de 1,80±0,04 m. El período de intervención varió de 3 a 15 semanas con el uso de 1 a 5 series de 5 a 10 repeticiones. Se ha demostrado que la mayoría de los protocolos proporcionan estímulos significativos para aumentar el nivel de cortisol de forma aguda (p<0,05). La práctica de entrenamiento de alta intensidad parece ser una intervención eficaz para estimular el aumento de los niveles de cortisol salival agudo y crónico y así inducir posibles cambios en los niveles fisiológicos y hormonales. Además, el cortisol parece representar la actividad física en algunas poblaciones y puede ser útil para monitorear la fisiología en encuestas observacionales de actividad física a gran escala. Sin embargo, se necesita más investigación para dilucidar los efectos de entrenamiento de alta intensidad sobre el cortisol y los resultados adaptativos.

Abstract. This study aimed to evaluate the effects of high-intensity training (HIT) on salivary cortisol levels in physically trained individuals. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations. The search for scientific articles was carried out on the Scopus and MEDLINE (via PubMed) databases with the terms resistance training, saliva, cortisol, and their synonyms. We included interventions with high-intense resistance training that analyzed the salivary cortisol levels in physically trained men and women. From the 399 articles found, eight studies met the inclusion criteria. A population of 135 physically trained men and 12 women is with an average age of 23.26 ± 3.10 years, body mass of 85.53 ± 12.68 kg, and height of 1.80 ± 0.04 m. The intervention period ranged from 3 to 15 weeks with the use of 1 to 5 sets of 5 to 10 repetitions. Most protocols have been shown to provide significant stimuli to increase the level of cortisol acutely (p<0.05). The practice of HIT seems to be an effective intervention to stimulate the increase in acute and chronic salivary cortisol levels and thus induce possible changes in physiological and hormonal levels. Moreover, cortisol seems to represent physical activity in some populations and may be useful in monitoring physiology in large-scale observational physical activity surveys. However, more research is needed to elucidate the effects of HIT on cortisol and adaptive results.


Adebero, T., McKinlay, B. J., Theocharidis, A., Root, Z., Josse, A. R., Klentrou, P., & Falk, B. (2020). Salivary and serum concentrations of cortisol and testosterone at rest and in response to intense exercise in boys versus men. Pediatric Exercise Science, 32(2), 65–72. https://doi.org/10.1123/pes.2019-0091

American College of Sports Medicine. (2017). ACSM’s guidelines for exercise testing and prescription. 10th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins.

Anderson, T., Haake, S., Lane, A. R., & Hackney, A. C. (2016). Changes in resting salivary testosterone, cortisol and interleukin-6 as biomarkers of overtraining. Baltic Journal of Sport & Health Sciences, 101(2), 2–7.

Arazi, H., Eghbali, E., Suzuki, K., & Mahdavi, M. (2019). Resistance exercise on two consecutive days induces cortisol, CK, IgA responses in active young males. Apunts. Medicina de l'Esport, 54(204), 131–138. https://doi.org/10.1016/j.apunts.2019.11.001

Bartolomei, S., Hoffman, J. R., Merni, F., & Stout, J. R. (2014). A comparison of traditional and block periodized strength training programs in trained athletes. Journal of Strength and Conditioning Research, 28(4), 990–997. http://doi.org/10.1519/JSC.0000000000000366

Becker, L., Semmlinger, L., & Rohleder, N. (2020). Resistance training as an acute stressor in healthy young men: associations with heart rate variability, alpha-amylase, and cortisol levels. International Journal on the Biology of Stress, 3, 1–13. http://doi.org/10.1080/10253890.2020.1799193

Berelleza, R. G., Trejo, M. T., Román, J. C. B., Alarcón Meza, E., Espejel, H. P., Millan, E. A., Hernández, G. S. R., & Riveros, L. C. (2020). Effect of a strength training program on IGF-1 in older adults with obesity and controlled hypertension. Retos, 39, 253–256. https://doi.org/10.47197/retos.v0i39.74723

Bonato, M., La Torre, A., Saresella, M., Marventano, I., Merati, G., & Vitale, J. A. (2017). Salivary cortisol concentration after high-intensity interval exercise: Time of day and chronotype effect. Chronobiology International, 34(6), 698–707. https://doi.org/10.1080/07420528.2017.1311336

Church, D. D., Hoffman, J. R., Mangine, G. T., Jajtner, A. R., Townsend, J. R., Beyer, K. S., et al. (2016). Comparison of high-intensity vs. high-volume resistance training on the BDNF response to exercise. Journal of Applied Physiology, 121(1), 123–128. https://doi.org/10.1152/japplphysiol.00233.2016

Cintineo, H. P., Freidenreich, D. J., Blaine, C.M., Cardaci, T.D., Pellegrino, J. K., & Arent, S. M. (2018). Acute physiological responses to an intensity-and time-under-tension-equated single- vs. Multiple-set resistance training bout in trained men. Journal of Strength and Conditioning Research, 32(12), 3310–3318. https://doi:10.1519/JSC.0000000000002872

Ciolac, E. G., & Silva, R. J. M. (2016). Resistance training as a tool for the prevention and treatment of musculoskeletal disorders. Sports Medicine, 46(9), 1239–1248. https://doi.org/10.1007/s40279-016-0507-Z

Crewther, B. T., & Christian, C. (2010). Relationships between salivary testosterone and cortisol concentrations and training performance in Olympic weightlifters. Journal of Sports Medicine and Physical Fitness, 50(3), 371–375.

Crewther, B. T., Cook, C., Cardinale, M., Weatherby, R. P., & Lowe, T. (2011). Two emerging concepts for elite athletes. Sports Medicine, 41(2), 103–123. https://doi.org/10.2165/11539170-000000000-00000

Crewther, B. T., Cook, C. J., Gaviglio, C. M., Kilduff, L. P., & Drawer, S. (2012). Baseline strength can influence the ability of salivary free testosterone to predict squat and sprinting performance. Journal of Strength and Conditioning Research, 26(1), 261–268. https://doi.org/10.1519/JSC.0b013e3182185158

Crewther, B. T., Heke, T., & Keogh, J. (2016). The effects of two equal-volume training protocols upon strength, body composition and salivary hormones in male rugby union players. Biology of Sport, 33(2), 111–116. https://doi.org/10.5604/20831862.1196511

Gaviglio, C. M., Kelly, V. G., Kilduff, L. P., & Cook, C. J. (2015). Salivary testosterone and cortisol responses to four different rugby training exercise protocols. European Journal of Sports Science, 15(6), 497–504. https://doi.org/10.1080/17461391.2015.1017012

Geisler, S., Aussieker, T., Paldauf, S., Scholz. S. Kur, Z. Jungs, S., Rissmeyer, M., Achtzehn, S., & Zinner, C. (2019). Salivary concentrations of testosterone and cortisol after two different resistance training exercises. Journal of Sports Medicine and Physical Fitness, 59(6), 1030–1035. https://doi.org/10.23736/S0022-4707.18.08786-8

Genner, K. M., & Weston, M. (2014). A comparison of workload quantification methods in relation to physiological responses to resistance exercise. Journal of Strength and Conditioning Research, 28(9), 2621–2627. https://doi.org/10.1519/JSC.0000000000000432

Klemp, A., Dolan, C., Quiles, J. M., Blanco, R., Zoeller, R. F., Graves, B. S., & Zourdos, M. C. (2016). Volume-equated high- and low-repetition daily undulating programming strategies produce similar hypertrophy and strength adaptations. Applied Physiology, Nutrition, and Metabolism, 41(7), 699–705. DOI: https://doi.org/10.1139/apnm-2015-0707

Liberati, A., Altman, D. G., Tetzlaff, J. Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., et al. (2009). The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. British Medical Journal, 339, b2700. https://doi.org/10.1136/bmj.b2700

Parastesh, M., Jalali, S. H., & Moradi, J. (2019). The effect of circadian rhythm on blood lactate concentration and salivary cortisol after one session of exhausting exercise in athlete girls. Razi Journal of Medical Sciences, 26(9), 59–67. http://rjms.iums.ac.ir/article-1-5477-en.html

Pineda-Espejel, H., Trejo, M., García, K., Garza, K., Vázquez-Jiménez, G., Machado-Contreras, J., Mejía-León, M., & Rodríguez, S. (2019). Salivary cortisol response and precompetitive anxiety in swimmers, Retos, 38(38), 1–7. https://doi.org/10.47197/retos.v38i38.72229

Radaelli, R., Fleck, S. J., Leite, T., Leite, R. D., Pinto, R. S., Fernandes, L., & Simão, R. (2015). Dose-response of 1, 3, and 5 sets of resistance exercise on strength, local muscular endurance, and hypertrophy. Journal of Strength and Conditioning Research, 29(5), 1349–1358. https://doi.org/10.1519/JSC.0000000000000758

Raya-González, J., Suárez-Arrones, L., Rísquez Bretones, A., & Sáez de Villarreal, E. (2017). Short-term effects of an eccentric-overload training program on the physical performance on U-16 elite soccer. Retos, 33, 106–111. https://doi.org/10.47197/retos.v0i33.53547

Sinclair, J., Wright, J., Hurst, H. T., Taylor, P. J., Atkins, S. (2013). The influence of circadian rhythms on peak isokinetic force of quadriceps and hamstring muscles. Isokinetics and Exercise Science, 21(4), 279–284. https://doi.org/10.3233/IES-130498

Sterne, J. A. C., Hernán, M. A., Reeves, B. C., Savović, J., Berkman, N. D., Viswanathan M., et al. (2016). ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. British Medical Journal, 355, i4919. https://doi.org/10.1136/bmj.i4919

Teo, W., Mcguigan, M. R., & Newton, M. J. (2011). The effects of circadian ritmetics of salivary cortisol and testosterone on maximum isometric strength, maximum dynamic strength and energy output. Journal of Strength and Conditioning Research, 25, 1538-1545. https://doi.org/10.1519/jsc.0b013e3181da77b0

Vale, R. G. S., Rosa, G., Nodari Junior, R. J., & Dantas, E. H. M. (2012). Cortisol and physical exercise. In: Esposito, A., & Bianchi, V. (Orgs.). Cortisol: physiology, regulation and health implications. New York: Nova Science Publishers.

Weakley, J. J. S., Till, K., Read, D. B., Roe, G. A. B., Darral-Jones, J., Phibbs, P. J., et al. (2017). The effects of traditional, superset, and tri-set resistance training structures on perceived intensity and physiological responses. European Journal of Applied Physiology, 117, 1877–1889. https://doi.org/10.1007/s00421-017-3680-3

Wilk, M., Petr, M., Krzysztofik, M., Zajac, A., & Stastny, P. (2018a). Endocrine response to high intensity barbell squats performed with constant movement tempo and variable training volume. Neuro Endocrinology Letters, 39(4), 342–348.

Wilk, M., Michalczyk, M., Golas, A., Krzysztofik, M., Maszczyk, A., & Zajac, A. (2018b). Endocrine responses following exhaustive strength exercise with and without the use of protein and protein-carbohydrate supplements. Biology of Sport, 35(4), 399–405. https://doi.org/10.5114/biolsport.2018.75754

Wunsch, K., Wursta, R., von Dawans, B., Strahler, J., Kasten, N., & Fuchs, R. (2019). Habitual and acute exercise effects on salivary biomarkers in response to psychosocial stress. Psychoneuroendocrinology, 106, 216–225. https://doi.org/10.1016/j.psyneuen.2019.03.015




Cómo citar

Aguiar, R. S., Lopes, G. C., Pinto de Castro, J. B., Prince, V. A., Mazini Filho, M. L., Nogueira da Gama, D. R., Moreira, R. A., Praxerdes, J. P., & Vale, R. G. (2021). Efectos del entrenamiento de resistencia de alta intensidad sobre el cortisol salival en individuos entrenados: una revisión sistemática (Effects of high-intense resistance training on salivary cortisol in trained individuals: a systematic review). Retos, 41, 265–271. https://doi.org/10.47197/retos.v0i41.82770



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