Preoperative staging MRI for rectal cancer and pathologic correlation
Keywords:
Cáncer de recto. RM. Correlación radiopatológica.Abstract
Background. Our aim is to asses the accuracy of MRI for preoperative rectal cancer staging and to establish a histopathologic correlation. Methods and materials. A retrospective analysis was performed on 120 patients aged between 43 and 87 with histologically proven rectal cancer who underwent MRI for preoperative staging in our hospital between 2005 and 2010. Patients were categorized according to the TNM classification. Results. Eighty of 120 patients underwent adjuvant chemoradiotheraphy because they had advanced disease (T3-T4), lymph node involvement (N1-N2) or resectable metastases. With 40 patients who didn’t undergo neoadjuvant therapy we performed a correlation between MRI and histopathological findings with a diagnostic accuracy in predicting T stage of 72%, N stage of 60% and distance to the mesorectal fascia of 87,5%. Conclusion. Pelvic MRI is a useful technique for locoregional staging of rectal cancer with a good radiopathologic correlation although the identification of nodal disease is still a diagnostic problem.Downloads
References
1. AYUSO COLELLA JR, PAGÉS LLINÁS M, AYUSO COLELLA C. [Estadificación del cáncer de recto]. Radiologia 2010; 52: 18-29.
https://doi.org/10.1016/j.rx.2009.11.001
2. IAFRATE F, LAGHI A, PAOLANTONIO P, RENGO M, MERCANTINI P, FERRI M et al. Preoperative staging of rectal cancer with MR Imaging: correlation with surgical and histopathologic findings. Radiographics 2006; 26: 701-714.
https://doi.org/10.1148/rg.263055086
3. HO ML, LIU J, NARRA V. Magnetic resonance imaging of rectal cancer. Clin Colon Rectal Surg 2008; 21: 178-187.
https://doi.org/10.1055/s-2008-1080997
4. MCMAHON CJ, SMITH MP. Magnetic resonance imaging in locoregional staging of rectal adenocarcinoma. Semin Ultrasound CT MR 2008; 29: 433-453.
https://doi.org/10.1053/j.sult.2008.10.008
5. BEETS-TAN RG, BEETS GL. Rectal cancer: review with emphasis on MR imaging. Radiology 2004; 232: 335-346.
https://doi.org/10.1148/radiol.2322021326
6. KLESSEN C, ROGALLA P, TAUPITZ M. Local staging of rectal cancer: the current role of MRI. Eur Radiol 2007; 17: 379-389.
https://doi.org/10.1007/s00330-006-0388-x
7. HO ML, LIU J, NARRA V. Magnetic resonance imaging of rectal cancer. Clin Colon Rectal Surg 2008; 21: 178-187.
https://doi.org/10.1055/s-2008-1080997
8. AKASU T, IINUMA G, FUJITA T, MURAMATSU Y, TATEISHI U, MIYAKAWA K. et al. Thin-section MRI with a phased-array coil for preoperative evaluation of pelvic anatomy and tumor extent in patients with rectal cancer. AJR 2005; 184: 531-538.
https://doi.org/10.2214/ajr.184.2.01840531
9. BIPAT S, GLAS AS, SLORS FJ, ZWINDERMAN AH, BOSSUYT PM, STOKER J. Rectal cancer: local staging and assessment of lymph node involvement with endoluminal US, CT, and MR imaging--a meta-analysis. Radiology 2004; 232: 773-783.
https://doi.org/10.1148/radiol.2323031368
10. TAYLOR FG, SWIFT RI, BLOMQVIST L, BROWN G. A systematic approach to the interpretation of preoperative staging MRI for rectal cancer. AJR 2008; 191: 1827-1835.
https://doi.org/10.2214/AJR.08.1004
11. BROWN G, RICHARDS CJ, BOURNE MW, NEWCOMBE RG, RADCLIFFE AG, DALLIMORE NS et al. Morphologic predictors of lymph node status in rectal cancer with use of high-spatial-resolution MR imaging with histopathologic comparison. Radiology 2003; 227: 371-377.
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