Eficacia y Efectividad de Ensayos Clínicos Aplicados al Tratamiento de la Obesidad: Una Revisión Sistemática (Efficacy and Effectiveness of Clinical Trials Applied to the Treatment of Obesity: A Systematic Review)

Autores/as

  • Greice Westphal-Nardo State University of Maringa https://orcid.org/0000-0001-9107-0108
  • Braulio Henrique Magnani Branco Cesumar University
  • Jean-Philippe Chaput Healthy Active Living and Obesity Research Group, Children’s Hospital of Eastern Ontario Research Institute https://orcid.org/0000-0002-5607-5736
  • Nelson Nardo Junior Center for Multiprofessional Studies on Obesity—NEMO/HUM/UEM, University Hospital of Maringa, State University of Maringa,

DOI:

https://doi.org/10.47197/retos.v53.102361

Palabras clave:

Obesidad, Tratamiento, Eficacia, Efectividad

Resumen

El tratamiento multidisciplinario de la obesidad (MTO) ha sido reconocido como la intervención estándar y la base para tratamientos complementarios. Sin embargo, aún no está claro cuán efectivos pueden ser los programas MTO, y se ha vuelto más difícil determinarlo porque normalmente las condiciones de la intervención no se especifican claramente. Por lo tanto, es importante aclarar si un programa MTO se caracteriza como un ensayo de eficacia, realizado en condiciones ideales, o como un ensayo de efectividad desarrollado en escenarios del mundo real. En este sentido, esta revisión sistemática tiene como objetivo explorar cierta información de los estudios MTO. Esta revisión sistemática realizó una búsqueda de posibles documentos utilizando PubMed y SciELO, en los cuales se presentaban los términos eficacia o efectividad. Después de aplicar todos los criterios de inclusión/exclusión, se incluyeron cuatro ensayos (343 participantes). Todos los estudios tenían características de ensayos de efectividad. Utilizaron tres resultados principales diferentes, lo que dificultó las comparaciones. En conclusión, esta revisión muestra que se ha publicado un número muy pequeño de estudios MTO utilizando la terminología eficacia o efectividad. Estos estudios no exploran los términos de una manera que podría hacer distinciones importantes entre estos diferentes modelos de ensayos clínicos.

Palabras clave: Obesidad; Tratamiento; Eficacia; Efectividad Efectividad.

Abstract. The multidisciplinary treatment of obesity (MTO) has been recognized as the standard intervention and the basis for complementary treatments. However, it is still not clear how effective MTO programs can be and it has become more difficult to determine because normally the conditions of the intervention are not clearly stated. Therefore, it is important to make it clear if one MTO program is characterized as an efficacy trial, conducted under ideal conditions, or as an effectiveness trial developed in real-world scenarios. In this sense, this systematic review aims to explore some information from MTO studies. This systematic review made a search for potential papers using PubMed and SciELO, in which the terms efficacy or effectiveness were presented. After applying all the inclusion/exclusion criteria, four trials were included (343 participants). All the studies had characteristics of effectiveness trials. They used three different main outcomes, which made comparisons difficult. In conclusion, this review shows that a very small number of MTO studies have been published using the terminology efficacy or effectiveness. These studies do not explore the terms in a way that could make important distinctions among these distinct clinical trial models.

Keywords: Obesity; Treatment; Efficacy; Effectiveness.

Biografía del autor/a

Greice Westphal-Nardo, State University of Maringa

PhD in Physical Education by the Associated Graduate Program in Physical Education UEM / UEL (2023) - in the area of concentration Human Performance and Physical Activity. In 2021 and 2022, she was a Researcher at the University of Ottawa with a CAPES scholarship from the Sandwich Doctorate Program Abroad - PDSE-CAPES in the city of Ottawa - Canada, at the Ottawa Hospital Research Institute and Children's Hospital of Eastern Ontario - CHEO, in the Healthy Active Living and Obesity Research Group - HALO. She is currently a Researcher at the Center for Multiprofessional Obesity Studies (NEMO). She is a member of the Canadian Obesity Network (CON). She was Engagement Coordinator in the program Optimizing the Treatment and Management of Obesity (OPTiMO) in partnership with MDBriefCase, in Toronto-Canada. She works mainly on the following topics: Obesity, Exercise Physiology, Evaluation and Functional Rehabilitation, Physical Activity, Cardiometabolic Risk, Research Methodology and Biostatistics.

Braulio Henrique Magnani Branco, Cesumar University

Possui licenciatura plena em Educação Física pela Universidade Estadual de Maringá (UEM) em 2005, bacharelado em Nutrição pela Universidade Cesumar (2021), mestrado em Ciências da Saúde pela UEM (2011) e doutorado em Ciências, pela Escola de Educação Física e Esporte da Universidade de São Paulo (EEFE-USP - 2016). Concluiu o pós-doutoramento no Centro de Investigação em Atividade Física, Saúde e Lazer (CIAFEL) na Faculdade de Desporto da Universidade do Porto em 2023. Atualmente, é professor associado da Universidade Cesumar e docente permanente do Programa de Pós-Graduação em Promoção da Saúde, em nível mestrado e doutorado, pela mesma instituição. É pesquisador do Instituto Cesumar de Ciência, Tecnologia e Inovação (ICETI) e editor adjunto da Revista Saúde e Pesquisa da UniCesumar. É membro da Sociedade Brasileira de Fisiologia e da Associação Brasileira para o Estudo da Obesidade e Síndrome Metabólica (ABESO), da Sociedade Brasileira de Fisiologia (SBFIS) e da Sociedade Brasileira de Atividade Física e Saúde (SBAFS). Apresenta colaborações com pesquisadores brasileiros, chilenos, canadenses, norte-americanos e portugueses. Tem experiência na área de Educação Física, atuando principalmente nos seguintes temas: Promoção da Saúde, Fisiologia do Exercício, Nutrição e Obesidade.

Jean-Philippe Chaput, Healthy Active Living and Obesity Research Group, Children’s Hospital of Eastern Ontario Research Institute

Dr. Chaput is a Senior Scientist with the Healthy Active Living and Obesity Research Group at the Children's Hospital of Eastern Ontario Research Institute and a Professor of Pediatrics at the University of Ottawa. His research focuses on obesity prevention, health promotion, and lifestyle behaviour modification (e.g., improving sleep, increasing physical activity, reducing screen time, and eating better). Dr. Chaput has published more than 400 peer-reviewed scientific articles and is well cited. He serves on many journal editorial boards and advisory committees, has contributed to a large number of conferences around the world (>200 lectures), and received several awards for his research. Outside work he likes to travel, run in the forest, and play with his daughter.

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Publicado

2024-04-01

Cómo citar

Westphal-Nardo, G., Magnani Branco, B. H., Chaput, J.-P., & Nardo Junior, N. (2024). Eficacia y Efectividad de Ensayos Clínicos Aplicados al Tratamiento de la Obesidad: Una Revisión Sistemática (Efficacy and Effectiveness of Clinical Trials Applied to the Treatment of Obesity: A Systematic Review). Retos, 53, 628–635. https://doi.org/10.47197/retos.v53.102361

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Vol. 53 (2024)

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Revisiones teóricas, sistemáticas y/o metaanálisis

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