Lung cancer in the Pontevedra health area: incidence, clinical presentation and survival

Authors

  • F.J. González-Barcala Hospital Clinico Universitario de Santiago de Compostela
  • J.A. Falagán
  • J.M. García-Prim
  • L. Valdés
  • J.M. Carreira
  • A. Puga
  • M.T. García-Sanz
  • D. Antón
  • J.C. Canive
  • A. Pose
  • R. López-López

Keywords:

Lung cancer. Diagnosis. Prognosis. Incidence. Treatment.

Abstract

Backgroud. To describe the clinical and epidemiological characteristics, and survival of patients with lung cancer (LC) in the Pontevedra Health Area.

Methods. A retrospective observational study was conducted on all patients with a diagnosis of LC in the Pontevedra Hospital Complex (CHOP) health area over a three-year period. The data recorded included, age, gender, smoking history, comorbidity, functional status, diagnostic method, histology type, stage, treatment received, and survival. The patients were followed up for 3 years.

Results. A total of 358 cases of LC were included in the study, which gave a crude incidence rate adjusted to the standard European population of 37.33/100,000 inhabitants/year in males and 4.88/100,000 inhabitants/year in females.

The large majority were males (87%). The mean age was 68.7 years, and 82% were smokers or ex-smokers. The most common histology type was epidermoid, with 35.2% of the cases.

The diagnosis was made in stages III-B or IV in 79% of cases. Chemotherapy was the first treatment in 53% of the cases. Survival after the first year was 25%, which decreased to 4% at the third year.

Conclusions. The incidence of LC in our health area continues to be mainly in male smokers, although the incidence in females and in people who never smoked is higher than in other populations in our country. It is diagnosed in the advance stages of the disease, and survival is poor.

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Author Biography

F.J. González-Barcala, Hospital Clinico Universitario de Santiago de Compostela

Especialista en Neumología

Servicio de Neumología-Hospital Clinico Universitario de Santiago de Compostela

Profesor colaborador-Universidad de Santiago de Compostela

References

1. CABANES A, VIDAL E, ARAGONÉS N, PÉREZ-GÓMEZ B, POLLÁN M, LOPE V et al Cancer mortality trends in Spain: 1980-2007. Ann Oncol 2010; 21 Suppl. 3: iii14-20.

https://doi.org/10.1093/annonc/mdq089

2. SÁNCHEZ MJ, PAYER T, DE ANGELIS R, LARRAÑAGA N, CAPOCACCIA R, MARTINEZ C. CIBERESP Working Group. Cancer incidence and mortality in Spain: estimates and projections for the period 1981-2012. Ann Oncol 2010; 21 Suppl 3: iii30-36.

https://doi.org/10.1093/annonc/mdq090

3. CHIRLAQUE MD, SALMERÓN D, ARDANAZ E, GALCERAN J, MARTÍNEZ R, MARCOS-GRAGERA R et al. Cancer survival in Spain: estimate for nine major cancers. Ann Oncol 2010; 21 Suppl 3: iii21-29.

https://doi.org/10.1093/annonc/mdq082

4. PRIM JM, BARCALA FJ, ESQUETE JP, REINO AP, LÓPEZ AF, CUADRADO LV. Lung cancer in a health area of Spain: incidence, characteristics and survival. Eur J Cancer Care (Engl) 2010; 19: 227-233.

https://doi.org/10.1111/j.1365-2354.2008.01008.x

5. MONTERO C, ROSALES M, OTERO I, BLANCO M, RODRÍGUEZ G, PETERGA S et al. Cáncer de pulmón en el Área Sanitaria de A Coruña: incidencia, abordaje clínico y supervivencia. Arch Bronconeumol 2003; 39: 209-216.

https://doi.org/10.1016/S0300-2896(03)75363-0

6. DE COS JS, MIRAVET L, ABAL J, NÚÑEZ A, MUÑOZ FJ, GARCÍA L et al. Lung cancer survival in Spain and prognostic factors: a prospective, multiregional study. Lung Cancer 2008; 59: 246-254.

https://doi.org/10.1016/j.lungcan.2007.08.013

7. JIMÉNEZ MASSA AE, ALONSO SARDÓN M, GÓMEZ GÓMEZ FP. Lung cancer: how does it appear in our hospital? Rev Clin Esp 2009; 209: 110-117.

https://doi.org/10.1016/S0014-2565(09)70876-8

8. HUETO PÉREZ DE HEREDIA J, CEBOLLERO RIVAS P, CASCANTE RODRIGO JA, ANDRADE VELA I, PASCAL MARTÍNEZ I et al. Evaluation of the use of a rapid diagnostic consultation of lung cancer. Delay Time of Diagnosis and Therapy. Arch Bronconeumol 2012; 48: 267-273.

https://doi.org/10.1016/j.arbres.2012.03.009

9. GULLÓN JA, SUÁREZ I, MEDINA A, MARTÍN A, CABRERA C, GONZÁLEZ IJ. Lung cancer: changes in epidemiology and survival. Rev Clin Esp 2012; 212: 18-23.

https://doi.org/10.1016/j.rce.2011.06.004

10. SALMERÓN D, CHIRLAQUE MD, ISABEL IZARZUGAZA M, SÁNCHEZ MJ, MARCOS-GRAGERA R, ARDANAZ E et al. Lung cancer prognosis in Spain: The role of histology, age and sex. Respir Med 2012; 106: 1301-1108.

https://doi.org/10.1016/j.rmed.2012.06.006

11. SAGERUP CM, SMÅSTUEN M, JOHANNESEN TB, HELLAND Å, BRUSTUGUN OT. Sex-specific trends in lung cancer incidence and survival: a population study of 40,118 cases. Thorax 2011; 66: 301-307.

https://doi.org/10.1136/thx.2010.151621

12. KLIGERMAN S, WHITE C. Epidemiology of lung cancer in women: risk factors, survival, and SCREENING. AJR Am J Roentgenol 2011; 196: 287-295.

https://doi.org/10.2214/AJR.10.5412

13. WORLD HEALTH Organization.The World Health Organization histologycal typing of lung tumors. Second edition. Am J Clin Pathol 1982; 77: 123-136.

https://doi.org/10.1093/ajcp/77.2.123

14. MOUNTAIN CF. Revisions in the internacional system for staging lung cancer. Chest 1997; 111: 1710.

https://doi.org/10.1378/chest.111.6.1710

15. RAMI PORTA R, DUQUE MEDINA JL, HERNÁNDEZ HERNÁNDEZ JR, LÓPEZ ENCUENTRA A, SÁNCHEZ DE COS ESCUIN J. Normativa actualizada (1998) sobre el diagnóstico y estadificación del carcinoma broncogénico. Recomendaciones SEPAR. Arch Bronconeumol 1998; 34: 437-452.

https://doi.org/10.1016/S0300-2896(15)30371-9

16. CHARLSON ME, POMPEI P, ALES KL, MACKENZIE CR. A new method of CLASSIFYING prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373-383.

https://doi.org/10.1016/0021-9681(87)90171-8

17. OKEN MM, CREECH RH, TORMEY DC, HORTON J, DAVIS TE, MCFADDEN ET et al. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 1982; 5: 649-655.

https://doi.org/10.1097/00000421-198212000-00014

18. JEMAL A, BRAY F, CENTER MM, FERLAY J, WARD E, FORMAN D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.

https://doi.org/10.3322/caac.20107

19. SHAFEY O, FERNÁNDEZ E, THUN M, SCHIAFFINO A, DOLWICK S, COKKINIDES V. Cigarette advertising and female smoking prevalence in Spain, 1982-1997: case studies in International Tobacco Surveillance. Cancer 2004; 100: 1744-1749.

https://doi.org/10.1002/cncr.20147

20. COURAUD S, ZALCMAN G, MILLERON B, MORIN F, SOUQUET PJ. Lung cancer in never smokers--a review. Eur J Cancer 2012; 48: 1299-1311.

https://doi.org/10.1016/j.ejca.2012.03.007

21. WHEATLEY-PRICE P, BLACKHALL F, LEE SM, MA C, ASHCROFT L, JITLAL M et al. The influence of sex and histology on outcomes in non-small-cell lung cancer: a pooled analysis of five randomized trials. Ann Oncol 2010; 21: 2023-2028.

https://doi.org/10.1093/annonc/mdq067

22. PARK SK, CHO LY, YANG JJ, PARK B, CHANG SH, LEE KS et al. Scientific Committee, Korean Academy of Tuberculosis and Respiratory Diseases. Lung cancer risk and cigarette smoking, lung tuberculosis according to histologic type and gender in a population based case-control study. Lung Cancer 2010; 68: 20-26.

https://doi.org/10.1016/j.lungcan.2009.05.017

23. BENDZSAK A, NENSHI R, DARLING G, SCHULTZ SE, GUNRAJ N, WILTON AS et al. Overview of lung cancer surgery in ontario. Ann Thorac Surg 2011; 91: 361-366.

https://doi.org/10.1016/j.athoracsur.2010.09.056

24. BEATTIE G, BANNON F, MCGUIGAN J. Lung cancer resection rates have increased significantly in females during a 15-year period. Eur J Cardiothorac Surg 2010; 38: 484-490.

https://doi.org/10.1016/j.ejcts.2010.03.004

25. SKAUG K, EIDE GE, GULSVIK A. Predictors of long-term survival of lung cancer patients in a Norwegian community. Clin Respir J 2011; 5: 50-58.

https://doi.org/10.1111/j.1752-699X.2010.00200.x

26. SVENSSON G, EWERS SB, OHLSSON O, OLSSON H. Prognostic factors in lung cancer in a defined geographical area over two decades with a special emphasis on gender. Clin Respir J. 2012, en prensa.

https://doi.org/10.1111/j.1752-699X.2012.00289.x

27. RIAZ SP, LÜCHTENBORG M, JACK RH, COUPLAND VH, LINKLATER KM, PEAKE MD et al. Variation in surgical resection for lung cancer in relation to survival: population-based study in England 2004-2006. Eur J Cancer 2012; 48: 54-60.

https://doi.org/10.1016/j.ejca.2011.07.012

28. IMPERATORI A, HARRISON RN, LEITCH DN, ROVERA F, LEPORE G, DIONIGI G, et al. Lung cancer in Teesside (UK) and Varese (Italy): a comparison of management and survival. Thorax 2006; 61: 232-239.

https://doi.org/10.1136/thx.2005.040477

29. BERGLUND A, LAMBE M, LÜCHTENBORG M, LINKLATER K, PEAKE MD, HOLMBERG L, et al. Social differences in lung cancer management and survival in South East England: a cohort study. BMJ Open 2012; 2(3).

https://doi.org/10.1136/bmjopen-2012-001048

30. GREGOR A, THOMSON CS, BREWSTER DH, STRONER PL, DAVIDSON J, FERGUSSON RJ et al; Scottish Cancer Trials Lung Group; Scottish Cancer Therapy Network. Management and survival of patients with lung cancer in Scotland diagnosed in 1995: results of a national population based study. Thorax 2001; 56: 212-217.

https://doi.org/10.1136/thorax.56.3.212

Published

2013-09-06

How to Cite

1.
González-Barcala F, Falagán J, García-Prim J, Valdés L, Carreira J, Puga A, et al. Lung cancer in the Pontevedra health area: incidence, clinical presentation and survival. An Sist Sanit Navar [Internet]. 2013 Sep. 6 [cited 2025 Dec. 6];36(2):217-2. Available from: https://recyt.fecyt.es/index.php/ASSN/article/view/24008525

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Research articles

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