El impacto del ejercicio aeróbico y de resistencia pesada en la aptitud física y las emociones las sobrevivientes de cáncer de mama experimentan cansancio relacionado con el cáncer
DOI:
https://doi.org/10.47197/retos.v67.111291Palabras clave:
cancer, physical activity, intensity training, body composition, physical fitnessResumen
Objetivo: Este estudio examinó cómo dos programas de ejercicios supervisados simultáneos afectaron a las sobrevivientes de cáncer de mama con cansancio inicial.
Metodología: Treinta y dos sobrevivientes de cáncer de mama, de 49 ± 4 años de edad, fueron asignadas aleatoriamente a programas de ejercicios aeróbicos (n = 16) o de ejercicios de resistencia intensos (n = 16). Ambos programas incluyeron dieciocho semanas de entrenamiento de resistencia, pero el componente aeróbico en el primero fue más vigoroso y supervisado, con una calificación de esfuerzo percibido de 7-8, en comparación con 6 para las intervenciones de ejercicios de resistencia intensos. La mayor parte del estudio abordó el cansancio percibido. Se midieron los puntos iniciales y finales a las dieciocho semanas. La corrección de Bonferroni para comparaciones múltiples colocó el nivel de significación estadística en 0,004.
Discusión: El programa de ejercicios aeróbicos y de resistencia pesada redujo la circunferencia de la cintura (p = 0,035) y otros parámetros antropométricos (p = 0,029). Los valores de p elevados en las comparaciones previas y posteriores a la intervención muestran que el ejercicio aeróbico no proporcionó estas ventajas. No se observaron diferencias significativas entre las terapias, ya que todos los valores de p superaron 0,004.
Conclusiones: En las sobrevivientes de cáncer de mama, se necesitan más investigaciones para determinar si el ejercicio de resistencia intenso concurrente es mejor que el aeróbico.
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Adams, S. C., Delorey, D. S., Davenport, M. H., Fairey, A. S., North, S., & Courneya, K. S. (2018). Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors. Brit-ish Journal of Cancer, 118(10). https://doi.org/10.1038/s41416-018-0044-7
Azab, B., Bhatt, V. R., Phookan, J., Murukutla, S., Kohn, N., Terjanian, T., & Widmann, W. D. (2012). Use-fulness of the neutrophil-to-lymphocyte ratio in predicting short- and long-term mortality in breast cancer patients. Annals of Surgical Oncology, 19(1). https://doi.org/10.1245/s10434-011-1814-0
Borg, G. A. V. (1954). Psychophysical bases of perceived exertion. Plastic and Reconstructive Surgery, 14(5).
Caan, B. J., Cespedes Feliciano, E. M., Prado, C. M., Alexeeff, S., Kroenke, C. H., Bradshaw, P., Quesenberry, C. P., Weltzien, E. K., Castillo, A. L., Olobatuyi, T. A., & Chen, W. Y. (2018). Association of muscle and adiposity measured by computed tomography with survival in patients with nonmetastatic breast cancer. JAMA Oncology, 4(6). https://doi.org/10.1001/jamaoncol.2018.0137
Cella, D., Davis, K., Breitbart, W., & Curt, G. (2001). Cancer-related fatigue: Prevalence of proposed diag-nostic criteria in a United States sample of cancer survivors. Journal of Clinical Oncology, 19(14). https://doi.org/10.1200/JCO.2001.19.14.3385
Chan, A. W., Tetzlaff, J. M., Gøtzsche, P. C., Altman, D. G., Mann, H., Berlin, J. A., Dickersin, K., Hróbjarts-son, A., Schulz, K. F., Parulekar, W. R., Krleža-Jerić, K., Laupacis, A., & Moher, D. (2024). SPIRIT 2013 explanation and elaboration: guidance for protocols of clinical trials. BMJ. https://doi.org/10.1136/bmj.e7586
Christensen, J. F., Jones, L. W., Andersen, J. L., Daugaard, G., Rorth, M., & Hojman, P. (2014). Muscle dys-function in cancer patients. In Annals of Oncology (Vol. 25, Issue 5). https://doi.org/10.1093/annonc/mdt551
Cleeland, C. S., Bennett, G. J., Dantzer, R., Dougherty, P. M., Dunn, A. J., Meyers, C. A., Miller, A. H., Payne, R., Reuben, J. M., Wang, X. S., & Lee, B. N. (2003). Are the symptoms of cancer and cancer treat-ment due to a shared biologic mechanism? A cytokine-immunologic model of cancer symp-toms. Cancer, 97(11). https://doi.org/10.1002/cncr.11382
Dibaba, D. T., Ogunsina, K., Braithwaite, D., & Akinyemiju, T. (2019). Metabolic syndrome and risk of breast cancer mortality by menopause, obesity, and subtype. Breast Cancer Research and Treatment, 174(1). https://doi.org/10.1007/s10549-018-5056-8
Echeverría, A. V., Rocha, T., Leite, J. C., Teixeira, P., & Cruz, O. (2016). Portuguese validation of the social competence and behavior evaluation scale (SCBE-30). Psicologia: Reflexao e Critica, 29(1). https://doi.org/10.1186/s41155-016-0014-z
Fayers, P., Bottomley, A., EORTC Quality of Life Group, & Quality of Life Unit. (2002). Quality of life research within the EORTC-the EORTC QLQ-C30. European Organisation for Research and Treatment of Cancer. European Journal of Cancer (Oxford, England : 1990), 38 Suppl 4.
Fu, T. C., Wang, C. H., Lin, P. S., Hsu, C. C., Cherng, W. J., Huang, S. C., Liu, M. H., Chiang, C. L., & Wang, J. S. (2013). Aerobic interval training improves oxygen uptake efficiency by enhancing cerebral and muscular hemodynamics in patients with heart failure. International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2011.11.086
Gadisa, D. A., Gebremariam, E. T., & Ali, G. Y. (2019). Reliability and validity of Amharic version of EORTC QLQ-C30 and QLQ-BR23 modules for assessing health-related quality of life among breast cancer patients in Ethiopia. Health and Quality of Life Outcomes, 17(1). https://doi.org/10.1186/s12955-019-1257-z
Gascón, P., Rodríguez, C. A., Valentín, V., Mata, J. G., Carulla, J., Cassinello, J., Colomer, R., & Baró, E. (2013). Usefulness of the PERFORM questionnaire to measure fatigue in cancer patients with anemia: A prospective, observational study. Supportive Care in Cancer, 21(11). https://doi.org/10.1007/s00520-013-1862-z
Grote, S., Almstedt, H. C., & Tarleton, H. P. (2016). Cardiometabolic health among cancer survivors: A 13-week pilot study of a combined aerobic and resistance training program. Oncology Nursing Forum, 43(3). https://doi.org/10.1188/16.ONF.306-315
Harriss, D. J., Macsween, A., & Atkinson, G. (2019). Ethical Standards in Sport and Exercise Science Re-search: 2020 Update. In International Journal of Sports Medicine (Vol. 40, Issue 13). https://doi.org/10.1055/a-1015-3123
Hwang, H. (2019). Influence of social cognitive factors on physical activity among breast cancer survi-vors. Korean Journal of Adult Nursing, 31(2). https://doi.org/10.7475/kjan.2019.31.2.211
Kang, S., Yoo, S., Baek, H., Lee, J., Choi, Y., Kim, H., Yi, H., & Yang, E. J. (2019). Potentials of Smart dyna-mometer use for clinical and self-management of rehabilitation in breast cancer survivors: a feasibility study. Biomedical Engineering Letters, 9(2). https://doi.org/10.1007/s13534-019-00101-3
Kilgour, R. D., Vigano, A., Trutschnigg, B., Hornby, L., Lucar, E., Bacon, S. L., & Morais, J. A. (2010). Can-cer-related fatigue: The impact of skeletal muscle mass and strength in patients with advanced cancer. Journal of Cachexia, Sarcopenia and Muscle, 1(2). https://doi.org/10.1007/s13539-010-0016-0
Klassen, O., Schmidt, M. E., Ulrich, C. M., Schneeweiss, A., Potthoff, K., Steindorf, K., & Wiskemann, J. (2017). Muscle strength in breast cancer patients receiving different treatment regimes. Journal of Cachexia, Sarcopenia and Muscle, 8(2). https://doi.org/10.1002/jcsm.12165
Lipsett, A., Barrett, S., Haruna, F., Mustian, K., & O’Donovan, A. (2017). The impact of exercise during adjuvant radiotherapy for breast cancer on fatigue and quality of life: A systematic review and meta-analysis. In Breast (Vol. 32). https://doi.org/10.1016/j.breast.2017.02.002
Mijwel, S., Backman, M., Bolam, K. A., Jervaeus, A., Sundberg, C. J., Margolin, S., Browall, M., Rundqvist, H., & Wengström, Y. (2018). Adding high-intensity interval training to conventional training mo-dalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial. Breast Cancer Research and Treatment, 168(1). https://doi.org/10.1007/s10549-017-4571-3
Moher, D., Schulz, K. F., Altman, D. G., & Lepage, L. (2001). The CONSORT statement: Revised recom-mendations for improving the quality of reports of parallel group randomized trials. In BMC Medical Research Methodology (Vol. 1). https://doi.org/10.1186/1471-2288-1-2
Molmen-Hansen, H. E., Stolen, T., Tjonna, A. E., Aamot, I. L., Ekeberg, I. S., Tyldum, G. A., Wisloff, U., In-gul, C. B., & Stoylen, A. (2012). Aerobic interval training reduces blood pressure and improves myocardial function in hypertensive patients. European Journal of Preventive Cardiology. https://doi.org/10.1177/1741826711400512
Montel, L., Ssenyonga, N., Coleman, M. P., & Allemani, C. (2022). How should implementation of the human right to health be assessed? A scoping review of the public health literature from 2000 to 2021. In International Journal for Equity in Health (Vol. 21, Issue 1). https://doi.org/10.1186/s12939-022-01742-0
Nakagawa, T., Fukui, T., Ohsumi, Y., Miyamoto, E., & Gotoh, M. (2023). Association between oxygen consumption and stepping exercise standardized with a triaxial accelerometer. General Thorac-ic and Cardiovascular Surgery, 71(1). https://doi.org/10.1007/s11748-022-01860-0
Neil, S. E., Klika, R. J., Garland, S. J., McKenzie, D. C., & Campbell, K. L. (2013). Cardiorespiratory and neu-romuscular deconditioning in fatigued and non-fatigued breast cancer survivors. Supportive Care in Cancer, 21(3). https://doi.org/10.1007/s00520-012-1600-y
Padilha, C. S., Marinello, P. C., Galvão, D. A., Newton, R. U., Borges, F. H., Frajacomo, F., & Deminice, R. (2017). Evaluation of resistance training to improve muscular strength and body composition in cancer patients undergoing neoadjuvant and adjuvant therapy: a meta-analysis. In Journal of Cancer Survivorship (Vol. 11, Issue 3). https://doi.org/10.1007/s11764-016-0592-x
Pagola Javier S.; Alejo Lidia B; Barcelo Olga; Montil Marta; Oliván Jesús; Alvarez-Bustos Alejandro; Can-tos Blanca; Maximiano Constanza; Hidalgo Francisco; Valenzuela Pedro L.; Fiuza-Luces Carmen; Lucia Alejandro; Ruiz-Casado Ana, I. M. (2020). Concurrent Exercise Interventions in Breast Cancer Survivors with Cancer-related Fatigue. International Journal of Sports Medicine, 41(11), 790–797. https://doi.org/10.1055/a-1147-1513
Peel, J. B., Sui, X., Adams, S. A., HIbert, J. R., Hardin, J. W., & Blair, S. N. (2009). A prospective study of car-diorespiratory fitness and breast cancer mortality. Medicine and Science in Sports and Exercise, 41(4). https://doi.org/10.1249/MSS.0b013e31818edac7
Perwitasari, D. A., Purba, F. D., Candradewi, S. F., Dania, H., Muhammad Irham, L., Noor Faridah, I., & Septiantoro, B. P. (2023). Quality of Life of Cancer Patients during Chemotherapy in Indonesia: A Comparison of EORTC QLQ-C30 and EQ-5D-5L, Based on Patients’ Characteristics. Interna-tional Journal of Clinical Practice, 2023. https://doi.org/10.1155/2023/9357299
Refiani, E., Maliza, R., Fitri, H., & Lestari, P. (2021). Therapeutic Effects of Medicinal Plants on Diabetic Foot Ulcers: A Systematic Review. Journal of Agromedicine and Medical Sciences, 7(3). https://doi.org/10.19184/ams.v7i3.24244
Rogers, L. Q., Vicari, S., Trammell, R., Hopkins-Price, P., Fogleman, A., Spenner, A., Rao, K., Courneya, K. S., Hoelzer, K. S., Robbs, R., & Verhulst, S. (2014). Biobehavioral factors mediate exercise effects on fatigue in breast cancer survivors. Medicine and Science in Sports and Exercise, 46(6). https://doi.org/10.1249/MSS.0000000000000210
Ruiz-Casado, A., Verdugo, A. S., Solano, M. J. O., Aldazabal, I. P., Fiuza-Luces, C., Alejo, L. B., Del Hierro, J. R. P., Palomo, I., Aguado-Arroyo, O., Garatachea, N., Cebolla, H., & Lucia, A. (2014). Objectively assessed physical activity levels in Spanish cancer survivors. Oncology Nursing Forum, 41(1). https://doi.org/10.1188/14.ONF.E12-E20
Ruiz-Ruiz, J., Mesa, J. L. M., Gutiérrez, A., & Castillo, M. J. (2002). Hand size influences optimal grip span in women but not in men. Journal of Hand Surgery, 27(5). https://doi.org/10.1053/jhsu.2002.34315
Saligan, L. N., Olson, K., Filler, K., Larkin, D., Cramp, F., Sriram, Y., Escalante, C. P., del Giglio, A., Kober, K. M., Kamath, J., Palesh, O., & Mustian, K. (2015). The biology of cancer-related fatigue: a review of the literature. In Supportive Care in Cancer (Vol. 23, Issue 8). https://doi.org/10.1007/s00520-015-2763-0
Schmidt, M. E., Chang-Claude, J., Vrieling, A., Heinz, J., Flesch-Janys, D., & Steindorf, K. (2012). Fatigue and quality of life in breast cancer survivors: Temporal courses and long-term pattern. Journal of Cancer Survivorship, 6(1). https://doi.org/10.1007/s11764-011-0197-3
Schmidt, M. E., Semik, J., Habermann, N., Wiskemann, J., Ulrich, C. M., & Steindorf, K. (2016). Cancer-related fatigue shows a stable association with diurnal cortisol dysregulation in breast cancer patients. Brain, Behavior, and Immunity, 52. https://doi.org/10.1016/j.bbi.2015.10.005
Scott, J. M., Zabor, E. C., Schwitzer, E., Koelwyn, G. J., Adams, S. C., Nilsen, T. S., Moskowitz, C. S., Matsou-kas, K., Iyengar, N. M., Dang, C. T., & Jones, L. W. (2018). Efficacy of exercise therapy on cardi-orespiratory fitness in patients with cancer: A systematic review and meta-analysis. In Journal of Clinical Oncology (Vol. 36, Issue 22). https://doi.org/10.1200/JCO.2017.77.5809
Sha, F., Zhuang, S., Zhou, L., Zhang, L., Yang, Y., Zhang, S., Jiang, Y., Qiu, G., Chen, C., Zheng, J., & Zhang, S. (2015). Biomarkers for cancer-related fatigue and adverse reactions to chemotherapy in lung cancer patients. Molecular and Clinical Oncology, 3(1). https://doi.org/10.3892/mco.2014.439
Shachar, S. S., Williams, G. R., Muss, H. B., & Nishijima, T. F. (2016). Prognostic value of sarcopenia in adults with solid tumours: A meta-analysis and systematic review. In European Journal of Can-cer (Vol. 57). https://doi.org/10.1016/j.ejca.2015.12.030
Sosa, E. S., Groeneveld, I. F., Gonzalez-Saiz, L., López-Mojares, L. M., Villa-Asensi, J. R., Gonzalez, M. I. B., Fleck, S. J., PIrez, M., & Lucia, A. (2012). Intrahospital weight and aerobic training in children with cystic fibrosis: A randomized controlled trial. Medicine and Science in Sports and Exercise, 44(1). https://doi.org/10.1249/MSS.0b013e318228c302
Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians, 71(3). https://doi.org/10.3322/caac.21660
Sweegers, M. G., Altenburg, T. M., Brug, J., May, A. M., Van Vulpen, J. K., Aaronson, N. K., Arbane, G., Bohus, M., Courneya, K. S., Daley, A. J., Galvao, D. A., Garrod, R., Griffith, K. A., Van Harten, W. H., Hayes, S. C., Herrero-Román, F., Kersten, M. J., Lucia, A., McConnachie, A., … Buffart, L. M. (2019). Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: A meta-analysis of individual patient data. In British Journal of Sports Medicine (Vol. 53, Issue 13). https://doi.org/10.1136/bjsports-2018-099191
Thornton, L. M., Andersen, B. L., & Blakely, W. P. (2010). The Pain, Depression, and Fatigue Symptom Cluster in Advanced Breast Cancer: Covariation With the Hypothalamic-Pituitary-Adrenal Axis and the Sympathetic Nervous System. Health Psychology, 29(3). https://doi.org/10.1037/a0018836
Toohey, K., Pumpa, K., McKune, A., Cooke, J., & Semple, S. (2018). High-intensity exercise interventions in cancer survivors: a systematic review exploring the impact on health outcomes. In Journal of Cancer Research and Clinical Oncology (Vol. 144, Issue 1). https://doi.org/10.1007/s00432-017-2552-x
Wang, Z., Yan, J., Meng, S., Li, J., Yu, Y., Zhang, T., Tsang, R. C. C., El-Ansary, D., Han, J., & Jones, A. Y. M. (2022). Reliability and validity of sit-to-stand test protocols in patients with coronary artery disease. Frontiers in Cardiovascular Medicine, 9. https://doi.org/10.3389/fcvm.2022.841453
Winters-Stone, K. M., Bennett, J. A., Nail, L., & Schwartz, A. (2008). Strength, physical activity, and age predict fatigue in older breast cancer survivors. Oncology Nursing Forum, 35(5). https://doi.org/10.1188/08.ONF.815-821
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