Osteonecrosis de los maxilares por bisfosfonatos. Actualización y puesta al día
DOI:
https://doi.org/10.23938/ASSN.0138Palabras clave:
Bisfosfonatos. Difosfonatos. Osteonecrosis mandibular. Osteoporosis. Cirugía bucalResumen
Los bisfosfonatos son unos fármacos ampliamente utilizados principalmente para la osteoporosis y también en oncología. Un efecto secundario o complicación de los mismos, desconocida hasta el año 2003, es la osteonecrosis de los maxilares. Se revisan, en este trabajo, las características químicas de los distintos bisfosfonatos, su posible mecanismo de acción, la potencia relativa, los productos comerciales existentes en el mercado farmacéutico español y sus indicaciones; igualmente se repasa la osteonecrosis de los maxilares en sus comienzos, su concepto, sus estadios clínicos, la razón por la que esta patología aparece en los maxilares, sus factores de riesgo, su incidencia, la actitud a tomar por los dentistas con los pacientes que toman bisfosfonatos, el tratamiento y la posible predicción de la osteonecrosis.Descargas
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