Epithelioid angiosarcoma of the gallbladder. Case report and review of the literature

Authors

  • P. Sánchez Acedo Complejo Hospitalario de Navarra
  • J. Herrera Cabezón Jefe de la Unidad de Cirugía Hepatobiliopancreática del Complejo Hospitalario de Navarra
  • A. Tarifa Castilla Adjunto Servicio Cirugía General del Complejo Hospitalario de Navarra
  • C. Zazpe Ripa Adjunto Servicio Cirugía General del Complejo Hospitalario de Navarra
  • J.M. Lera Tricas Especialista Cirugía General del Complejo Hospitalario de Navarra. Secretario general del Sindicato Médico de Navarra

DOI:

https://doi.org/10.23938/ASSN.0085

Keywords:

Epithelioid angiosarcoma. Neoplasia. Biliary gallbladder.

Abstract

Angiosarcoma of the gallbladder is an infrequent pathology but has a high morbidity and mortality. There are only 10 references in the international literature.

We present a case treated in our center and we review the cases published since 1956.

An 81 year-old male patient with abdominal pain, asthenia and dyspnea. Analytically anemia and leukocytosis.  Exploration found a distended abdomen, right hypochondrium pain, with defense. Abdominal echography and a CT were requested with a diagnosis of acute cholecystitis and he was admitted for antibiotic treatment. The patient did not evolve favorably and was subjected to emergency surgery, which found a haemoperitoneum and a gallbladder with a tumoral appearance that could not be totally extirpated. He died 20 days after the operation. The report from pathological anatomy was compatible with epithelioid angiosarcoma of the biliary gallbladder.

Gallbladder angiosarcoma is a neoplasia with a bad prognosis, whose clinical presentation can be mistaken for acute cholecystitis. Improving the prognosis of this disease involves carrying out early diagnosis and surgical treatment.

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Author Biography

P. Sánchez Acedo, Complejo Hospitalario de Navarra

Residente Cirugía General Complejo Hospitalario de Navarra

References

1. BELELLI E. Case of primary angiosarcoma of the gallbladder. Ann Ital Chir 1956; 33: 1101-1114.

2. VAITTINEN E. Sarcoma of the gall-bladder. Ann Chir Gynaecol Fenn 1972; 61: 185-189.

3. ROSANSKY SJ, MULLENS CC. The hepatorenal syndrome associated with metastatic angiosarcoma of the gallbladder. Ann Intern Med 1982; 96: 191-192.

https://doi.org/10.7326/0003-4819-96-2-191

4. KAWAI T, HIROSE Y, AINOTA T, MIYAZAKI Y, YAMAMOTO Y, IKEDA M et al. A case of hemangiosarcoma of the gallbladder. Nihon Shokakibyo Gakkai Zasshi Jpn. J Gastro-Enterol 1989; 86: 2611-2616.

5. KUMAR A, LAL BK, SINGH MK, KAPUR BM. Angiosarcoma of the gallbladder. Am J Gastroenterol 1989; 84: 1431-1433.

6. HITTMAIR A, SANDBICHLER P, TÖTSCH M, MIKUZ G, SCHMID KW. Primary angiosarcoma of the gallbladder. Case report with review of the literature. Pathol 1991; 12: 279-281.

7. WHITE J, CHAN YF. Epithelioid angiosarcoma of the gallbladder. Histopathology 1994; 24: 269-271.

https://doi.org/10.1111/j.1365-2559.1994.tb00520.x

8. KUMAR A, SINGH MK, KAPUR BM. Synchronous double malignant tumors of the gall bladder. A case-report of squamous cell carcinoma with an angiosarcoma. Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol 1994; 20: 63-67.

9. ODASHIRO AN, PEREIRA PR, ODASHIRO MIIJI LN, NGUYEN GK. Angiosarcoma of the gallbladder: case report and review of the literature. Can J Gastroenterol J Can Gastroenterol 2005; 19: 257-259.

https://doi.org/10.1155/2005/794869

10. COSTANTINI R, DI BARTOLOMEO N, FRANCOMANO F, ANGELUCCI D, INNOCENTI P. Epithelioid angiosarcoma of the gallbladder: case report. J Gastrointest Surg Off J Soc Surg Aliment 2005 Tract 9, 822-825.

https://doi.org/10.1016/j.gassur.2005.01.286

Published

2015-08-30

How to Cite

1.
Sánchez Acedo P, Herrera Cabezón J, Tarifa Castilla A, Zazpe Ripa C, Lera Tricas J. Epithelioid angiosarcoma of the gallbladder. Case report and review of the literature. An Sist Sanit Navar [Internet]. 2015 Aug. 30 [cited 2025 Dec. 30];38(2):333-7. Available from: https://recyt.fecyt.es/index.php/ASSN/article/view/31921

Issue

Section

Clinical notes

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