Efectos de la suplementación con zumo de remolacha sobre la respuesta neuromuscular: revisión sistemática (Effect of beet juice supplementation (BJ) on neuromuscular response: a systematic review)

Autores/as

DOI:

https://doi.org/10.47197/retos.v0i39.79650

Palabras clave:

Entrenamiento de fuerza, Óxido nítrico, Resistencia muscular, Zumo de remolacha., (Beetroot; Muscular endurance; Nitric Oxide; Nitrate; Nitrite; Resistance training; Strength)

Resumen

 

El zumo de remolacha (ZR) es una fuente nutricional rica en nitrato (NO3-) que, una vez ingerido, es reducido a óxido nítrico (ON). El ON posee efectos hipotensores, anti-inflamatorios y provoca mejoras en la eficiencia mitocondrial y en la regulación de la contractilidad muscular. Distintas investigaciones han comprobado que la suplementación con ZR presenta un efecto ergogénico en modalidades de resistencia cardiorrespiratoria y esfuerzos explosivos e intermitentes de alta intensidad. Sin embargo, dado que ninguna revisión ha valorado el efecto de la suplementación con ZR sobre la producción de fuerza muscular, el objetivo de la presente revisión sistemática es analizar el efecto de la suplementación con ZR sobre el rendimiento en la fuerza muscular. La búsqueda mediante palabras clave y conectores booleanos se realizó en las bases de datos Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus y SPORTDiscus. La estrategia de búsqueda empleada fue la siguiente: (nitrate OR beet*) AND (concepto 2) (supplement* OR nutr* OR diet*) AND (concepto 3) (strength OR "resistance exercise" OR "resistance training" OR "muscular power"). Tras la aplicación de los criterios de inclusión, un total de 14 artículos fueron seleccionados para la revisión. En la revisión se ha comprobado como la suplementación con ZR puede tener un efecto ergogénico sobre la producción de fuerza muscular bajo estimulación eléctrica, así como sobre la producción de potencia sobre contracciones isocinéticas únicamente a altas velocidades angulares, siendo el mecanismo explicativo una potenciación de la capacidad contráctil específicamente en las fibras musculares tipo II.

Abstract. Beet juice (BJ) is a nutritional source rich in nitrate (NO3-) which, after ingestion, is reduced to nitric oxide (NO). NO has effects such as reduction in arterial pressure, anti-inflammatory effects, enhancement of mitochondrial efficiency, and regulation of muscle contractility. Different studies have reported that BJ supplementation has an ergogenic effect in modalities of cardiorespiratory endurance and explosive and intermittent high intensity efforts. Nevertheless, no review has assessed the effect of BJ supplementation on muscle strength production. Thus, the objective of this systematic review is to analyse the effect of BJ supplementation on muscle strength performance. The search using keywords and Boolean connectors was carried out in the databases Dialnet, Directory of Open Access Journals, Medline, Pubmed, Scielo, Scopus, and SPORTDiscus. The search strategy used was the following: (nitrate OR beet *) AND (concept 2) (supplement * OR nutr * OR diet *) AND (concept 3) (strength OR "resistance exercise" OR "resistance training" OR "muscular power "). After the application of the inclusion criteria, a total of 14 articles were selected for review. The review has shown how BJ supplementation can have an ergogenic effect on the production of muscle strength under electrical stimulation, as well as on the production of power over isokinetic contractions only at high angular speeds, the explanatory mechanism being a potentiation of the contractile capacity specifically in type II muscle fibers.

Biografía del autor/a

Juan José Ramos Álvarez , Universidad Complutense de Madrid

Especialista en Medicina de la Educación Física y el Deporte. Escuela de Medicina del Deporte. Departamento de Radiología, Rehabilitación y Fisioterapia. Universidad Complutense de Madrid

Juan José Montoya Miñano , Universidad Complutense de Madrid

Especialista en Medicina de la Educación Física y el Deporte. Escuela de Medicina del Deporte. Departamento de Radiología, Rehabilitación y Fisioterapia. Universidad Complutense de Madrid

Francisco Miguel Tobal , Universidad Complutense de Madrid

Especialista en Medicina de la Educación Física y el Deporte. Escuela de Medicina del Deporte. Departamento de Radiología, Rehabilitación y Fisioterapia. Universidad Complutense de Madrid

Pablo Jodrá Jiménez , Universidad de Alcalá de Henares. Madrid

Doctor en Ciencias de la Actividad Física y el Deporte. Psicólogo. Departamento de Psicología Evolutiva y de la Educación. Universidad de Alcalá de Henares. Madrid

Raul Domínguez , Universidad Isabel I

Doctor en Ciencias de la Actividad Física y el Deporte. Facultad de Ciencias de la Salud de la Universidad Isabel I

Citas

Bailey, S. J., Fulford, J., Vanhatalo, A., Winyard, P. G., Blackwell, J. R., DiMenna, F. J., . . . Jones, A. M. (2010). Dietary nitrate supplementation enhances muscle contractile efficiency during knee-extensor exercise in humans. J Appl Physiol (1985), 109(1), 135-148. doi:10.1152/japplphysiol.00046.2010

Bailey, S. J., Vanhatalo, A., Winyard, P. G., & Jones, A. M. (2011). The nitrate-nitrite-nitric oxide pathway: Its role in human exercise physiology. Eur J Sport Sci, 12(4), 309-320.

Barclay, C. J., Woledge, R. C., & Curtin, N. A. (2007). Energy turnover for Ca2+ cycling in skeletal muscle. J Muscle Res Cell Motil, 28(4-5), 259-274. doi:10.1007/s10974-007-9116-7

Bender, D., Townsend, J. R., Vantrease, W. C., Marshall, A. C., Henry, R. N., Heffington, S. H., & Johnson, K. D. (2018). Acute beetroot juice administration improves peak isometric force production in adolescent males. Appl Physiol Nutr Metab, 43(8), 816-821. doi:10.1139/apnm-2018-0050

Buckthorpe, M. W., Hannah, R., Pain, T. G., & Folland, J. P. (2012). Reliability of neuromuscular measurements during explosive isometric contractions, with special reference to electromyography normalization techniques. Muscle Nerve, 46(4), 566-576. doi:10.1002/mus.23322

Castro Jiménez, L. E., Gálvez Pardo, A. Y., Guzmán Quintero, G. A., & Garcia Muñoz, A. I. (2019). Fuerza explosiva en adultas mayores, efectos del entrenamiento en fuerza máxima. Retos, 36, 64-68.

Coggan, A. R., Hoffman, R. L., Gray, D. A., Moorthi, R. N., Thomas, D. P., Leibowitz, J. L., . . . Peterson, L. R. (2019). A single dose of dietary nitrate increases maximal knee extensor angular velocity and power in healthy older men and women. J Gerontol A Biol Sci Med Sci. doi:10.1093/gerona/glz156

Coggan, A. R., Leibowitz, J. L., Kadkhodayan, A., Thomas, D. P., Ramamurthy, S., Spearie, C. A., . . . Peterson, L. R. (2015). Effect of acute dietary nitrate intake on maximal knee extensor speed and power in healthy men and women. Nitric Oxide, 48, 16-21. doi:10.1016/j.niox.2014.08.014

Coggan, A. R., Leibowitz, J. L., Spearie, C. A., Kadkhodayan, A., Thomas, D. P., Ramamurthy, S., . . . Peterson, L. R. (2015). Acute Dietary Nitrate Intake Improves Muscle Contractile Function in Patients With Heart Failure: A Double-Blind, Placebo-Controlled, Randomized Trial. Circ Heart Fail, 8(5), 914-920. doi:10.1161/CIRCHEARTFAILURE.115.002141

Crewther, B., Cronin, J., & Keogh, J. (2006). Possible stimuli for strength and power adaptation : acute metabolic responses. Sports Med, 36(1), 65-78. doi:10.2165/00007256-200636010-00005

Cuenca, E., Jodra, P., Perez-Lopez, A., Gonzalez-Rodriguez, L. G., Fernandes da Silva, S., Veiga-Herreros, P., & Dominguez, R. (2018). Effects of Beetroot Juice Supplementation on Performance and Fatigue in a 30-s All-Out Sprint Exercise: A Randomized, Double-Blind Cross-Over Study. Nutrients, 10(9). doi:10.3390/nu10091222

Dominguez, R., Cuenca, E., Mate-Munoz, J. L., Garcia-Fernandez, P., Serra-Paya, N., Estevan, M. C., . . . Garnacho-Castano, M. V. (2017). Effects of Beetroot Juice Supplementation on Cardiorespiratory Endurance in Athletes. A Systematic Review. Nutrients, 9(1). doi:10.3390/nu9010043

Dominguez, R., Garnacho-Castano, M. V., Cuenca, E., Garcia-Fernandez, P., Munoz-Gonzalez, A., de Jesus, F., . . . Mate-Munoz, J. L. (2017). Effects of Beetroot Juice Supplementation on a 30-s High-Intensity Inertial Cycle Ergometer Test. Nutrients, 9(12). doi:10.3390/nu9121360

Domínguez, R., Garnacho-Castaño, M. V., & Maté-Muñoz, J. L. (2016). Efectos del entrenamiento contra resistencias o resistance training en diversas patologías. Nutr Hosp, 33(3), 719-733.

Dominguez, R., Mate-Munoz, J. L., Cuenca, E., Garcia-Fernandez, P., Mata-Ordonez, F., Lozano-Estevan, M. C., . . . Garnacho-Castano, M. V. (2018). Effects of beetroot juice supplementation on intermittent high-intensity exercise efforts. J Int Soc Sports Nutr, 15, 2. doi:10.1186/s12970-017-0204-9

Duke, A. M., & Steele, D. S. (2001). Mechanisms of reduced SR Ca(2+) release induced by inorganic phosphate in rat skeletal muscle fibers. Am J Physiol Cell Physiol, 281(2), C418-429. doi:10.1152/ajpcell.2001.281.2.C418

Ferguson, S. K., Hirai, D. M., Copp, S. W., Holdsworth, C. T., Allen, J. D., Jones, A. M., . . . Poole, D. C. (2013). Impact of dietary nitrate supplementation via beetroot juice on exercising muscle vascular control in rats. J Physiol, 591(2), 547-557. doi:10.1113/jphysiol.2012.243121

Ferguson, S. K., Holdsworth, C. T., Wright, J. L., Fees, A. J., Allen, J. D., Jones, A. M., . . . Poole, D. C. (2015). Microvascular oxygen pressures in muscles comprised of different fiber types: Impact of dietary nitrate supplementation. Nitric Oxide, 48, 38-43. doi:10.1016/j.niox.2014.09.157

Flanagan, S. D., Looney, D. P., Miller, M. J., DuPont, W. H., Pryor, L., Creighton, B. C., . . . Kraemer, W. J. (2016). The Effects of Nitrate-Rich Supplementation on Neuromuscular Efficiency during Heavy Resistance Exercise. J Am Coll Nutr, 35(2), 100-107. doi:10.1080/07315724.2015.1081572

Folland, J. P., Buckthorpe, M. W., & Hannah, R. (2014). Human capacity for explosive force production: neural and contractile determinants. Scand J Med Sci Sports, 24(6), 894-906. doi:10.1111/sms.12131

Fry, A. C. (2004). The role of resistance exercise intensity on muscle fibre adaptations. Sports Med, 34(10), 663-679. doi:10.2165/00007256-200434100-00004

Fulford, J., Winyard, P. G., Vanhatalo, A., Bailey, S. J., Blackwell, J. R., & Jones, A. M. (2013). Influence of dietary nitrate supplementation on human skeletal muscle metabolism and force production during maximum voluntary contractions. Pflugers Arch, 465(4), 517-528. doi:10.1007/s00424-013-1220-5

Hackett, D., Davies, T., Soomro, N., & Halaki, M. (2016). Olympic weightlifting training improves vertical jump height in sportspeople: a systematic review with meta-analysis. Br J Sports Med, 50(14), 865-872. doi:10.1136/bjsports-2015-094951

Haider, G., & Folland, J. P. (2014). Nitrate supplementation enhances the contractile properties of human skeletal muscle. Med Sci Sports Exerc, 46(12), 2234-2243. doi:10.1249/MSS.0000000000000351

Hernandez, A., Schiffer, T. A., Ivarsson, N., Cheng, A. J., Bruton, J. D., Lundberg, J. O., . . . Westerblad, H. (2012). Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle. J Physiol, 590(15), 3575-3583. doi:10.1113/jphysiol.2012.232777

Hopkins, W. G., Hawley, J. A., & Burke, L. M. (1999). Design and analysis of research on sport performance enhancement. Med Sci Sports Exerc, 31(3), 472-485. doi:10.1097/00005768-199903000-00018

Ivy, J. L., Withers, R. T., Brose, G., Maxwell, B. D., & Costill, D. L. (1981). Isokinetic contractile properties of the quadriceps with relation to fiber type. Eur J Appl Physiol Occup Physiol, 47(3), 247-255. doi:10.1007/bf00422470

Johnson, M. A., Polgar, J., Weightman, D., & Appleton, D. (1973). Data on the distribution of fibre types in thirty-six human muscles. An autopsy study. J Neurol Sci, 18(1), 111-129. doi:10.1016/0022-510x(73)90023-3

Jones, A. M. (2014). Dietary nitrate supplementation and exercise performance. Sports Med, 44 Suppl 1, S35-45. doi:10.1007/s40279-014-0149-y

Jones, A. M., Ferguson, S. K., Bailey, S. J., Vanhatalo, A., & Poole, D. C. (2016). Fiber Type-Specific Effects of Dietary Nitrate. Exerc Sport Sci Rev, 44(2), 53-60. doi:10.1249/JES.0000000000000074

Justice, J. N., Gioscia-Ryan, R. A., Johnson, L. C., Battson, M. L., de Picciotto, N. E., Beck, H. J., . . . Seals, D. R. (2015). Sodium nitrite supplementation improves motor function and skeletal muscle inflammatory profile in old male mice. J Appl Physiol (1985), 118(2), 163-169. doi:10.1152/japplphysiol.00608.2014

Kawasaki, T., & Kasai, M. (1994). Regulation of calcium channel in sarcoplasmic reticulum by calsequestrin. Biochem Biophys Res Commun, 199(3), 1120-1127. doi:10.1006/bbrc.1994.1347

Kokkinoplitis, K., & Chester, N. J. (2014). The effect of beetroot juice on repeated sprint performance and muscle force production. J. Phys. Educ. Sport, 14(2), 242-247.

Koncic, M. Z., & Tomczyk, M. (2013). New insights into dietary supplements used in sport: active substances, pharmacological and side effects. Curr Drug Targets, 14(9), 1079-1092. doi:10.2174/1389450111314090016

Larsen, F. J., Schiffer, T. A., Borniquel, S., Sahlin, K., Ekblom, B., Lundberg, J. O., & Weitzberg, E. (2011). Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab, 13(2), 149-159. doi:10.1016/j.cmet.2011.01.004

Larsen, F. J., Weitzberg, E., Lundberg, J. O., & Ekblom, B. (2010). Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise. Free Radic Biol Med, 48(2), 342-347. doi:10.1016/j.freeradbiomed.2009.11.006

Lauersen, J. B., Andersen, T. E., & Andersen, L. B. (2018). Strength training as superior, dose-dependent and safe prevention of acute and overuse sports injuries: a systematic review, qualitative analysis and meta-analysis. Br J Sports Med, 52(24), 1557-1563. doi:10.1136/bjsports-2018-099078

Lee, S., Abel, M. G., Thomas, T., Symons, T. B., & Yates, J. W. (2019). Acute beetroot juice supplementation does not attenuate knee extensor exercise muscle fatigue in a healthy young population. J Exerc Nutrition Biochem, 23(1), 55-62. doi:10.20463/jenb.2019.0008

Lopez-Gonzalez, L. M., Sanchez-Oliver, A. J., Mata, F., Jodra, P., Antonio, J., & Dominguez, R. (2018). Acute caffeine supplementation in combat sports: a systematic review. J Int Soc Sports Nutr, 15(1), 60. doi:10.1186/s12970-018-0267-2

Maher, C. G., Sherrington, C., Herbert, R. D., Moseley, A. M., & Elkins, M. (2003). Reliability of the PEDro scale for rating quality of randomized controlled trials. Phys Ther, 83(8), 713-721. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/12882612

Maughan, R. J., Burke, L. M., Dvorak, J., Larson-Meyer, D. E., Peeling, P., Phillips, S. M., . . . Engebretsen, L. (2018). IOC consensus statement: dietary supplements and the high-performance athlete. Br J Sports Med, 52(7), 439-455. doi:10.1136/bjsports-2018-099027

McCrary, J. M., Ackermann, B. J., & Halaki, M. (2015). A systematic review of the effects of upper body warm-up on performance and injury. Br J Sports Med, 49(14), 935-942. doi:10.1136/bjsports-2014-094228

McMahon, N. F., Leveritt, M. D., & Pavey, T. G. (2017). The Effect of Dietary Nitrate Supplementation on Endurance Exercise Performance in Healthy Adults: A Systematic Review and Meta-Analysis. Sports Med, 47(4), 735-756. doi:10.1007/s40279-016-0617-7

Modin, A., Bjorne, H., Herulf, M., Alving, K., Weitzberg, E., & Lundberg, J. O. (2001). Nitrite-derived nitric oxide: a possible mediator of 'acidic-metabolic' vasodilation. Acta Physiol Scand, 171(1), 9-16. doi:10.1046/j.1365-201X.2001.00771.x

Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., . . . Group, P.-P. (2015). Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev, 4, 1. doi:10.1186/2046-4053-4-1

Mosher, S. L., Sparks, S. A., Williams, E. L., Bentley, D. J., & Mc Naughton, L. R. (2016). Ingestion of a Nitric Oxide Enhancing Supplement Improves Resistance Exercise Performance. J Strength Cond Res, 30(12), 3520-3524. doi:10.1519/JSC.0000000000001437

Ormer, N., Rodhilla, A., Rodhilla, S., & Kushnoor, A. (2012). Nitric Oxide: Role in Human Biology. Int. j. pharm. sci. drug. res., 4(2), 105-109.

Smith, R. A., Martin, G. J., Szivak, T. K., Comstock, B. A., Dunn-Lewis, C., Hooper, D. R., . . . Kraemer, W. J. (2014). The effects of resistance training prioritization in NCAA Division I Football summer training. J Strength Cond Res, 28(1), 14-22. doi:10.1519/JSC.0b013e3182977e56

Szentesi, P., Zaremba, R., van Mechelen, W., & Stienen, G. J. (2001). ATP utilization for calcium uptake and force production in different types of human skeletal muscle fibres. J Physiol, 531(Pt 2), 393-403. doi:10.1111/j.1469-7793.2001.0393i.x

Thompson, C., Vanhatalo, A., Jell, H., Fulford, J., Carter, J., Nyman, L., . . . Jones, A. M. (2016). Dietary nitrate supplementation improves sprint and high-intensity intermittent running performance. Nitric Oxide, 61, 55-61. doi:10.1016/j.niox.2016.10.006

Tillin, N. A., Jimenez-Reyes, P., Pain, M. T., & Folland, J. P. (2010). Neuromuscular performance of explosive power athletes versus untrained individuals. Med Sci Sports Exerc, 42(4), 781-790. doi:10.1249/MSS.0b013e3181be9c7e

Tillin, N. A., Moudy, S., Nourse, K. M., & Tyler, C. J. (2018). Nitrate Supplement Benefits Contractile Forces in Fatigued but Not Unfatigued Muscle. Med Sci Sports Exerc, 50(10), 2122-2131. doi:10.1249/MSS.0000000000001655

Totzeck, M., Hendgen-Cotta, U. B., Luedike, P., Berenbrink, M., Klare, J. P., Steinhoff, H. J., . . . Rassaf, T. (2012). Nitrite regulates hypoxic vasodilation via myoglobin-dependent nitric oxide generation. Circulation, 126(3), 325-334. doi:10.1161/CIRCULATIONAHA.111.087155

Trexler, E. T., Keith, D. S., Schwartz, T. A., Ryan, E. D., Stoner, L., Persky, A. M., & Smith-Ryan, A. E. (2019). Effects of Citrulline Malate and Beetroot Juice Supplementation on Blood Flow, Energy Metabolism, and Performance During Maximum Effort Leg Extension Exercise. J Strength Cond Res, 33(9), 2321-2329. doi:10.1519/JSC.0000000000003286

van Tulder, M., Furlan, A., Bombardier, C., Bouter, L., & Editorial Board of the Cochrane Collaboration Back Review, G. (2003). Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine (Phila Pa 1976), 28(12), 1290-1299. doi:10.1097/01.BRS.0000065484.95996.AF

Vandenboom, R., Grange, R. W., & Houston, M. E. (1993). Threshold for force potentiation associated with skeletal myosin phosphorylation. Am J Physiol, 265(6 Pt 1), C1456-1462. doi:10.1152/ajpcell.1993.265.6.C1456

Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Pavey, T. G., Wilkerson, D. P., . . . Jones, A. M. (2010). Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise. Am J Physiol Regul Integr Comp Physiol, 299(4), R1121-1131. doi:10.1152/ajpregu.00206.2010

Viner, R. I., Williams, T. D., & Schoneich, C. (2000). Nitric oxide-dependent modification of the sarcoplasmic reticulum Ca-ATPase: localization of cysteine target sites. Free Radic Biol Med, 29(6), 489-496. doi:10.1016/s0891-5849(00)00325-7

Whitfield, J., Gamu, D., Heigenhauser, G. J. F., LJC, V. A. N. L., Spriet, L. L., Tupling, A. R., & Holloway, G. P. (2017). Beetroot Juice Increases Human Muscle Force without Changing Ca2+-Handling Proteins. Med Sci Sports Exerc, 49(10), 2016-2024. doi:10.1249/MSS.0000000000001321

Wickham, K. A., McCarthy, D. G., Pereira, J. M., Cervone, D. T., Verdijk, L. B., van Loon, L. J. C., . . . Spriet, L. L. (2019). No effect of beetroot juice supplementation on exercise economy and performance in recreationally active females despite increased torque production. Physiol Rep, 7(2), e13982. doi:10.14814/phy2.13982

Wylie, L. J., Mohr, M., Krustrup, P., Jackman, S. R., Ermiotadis, G., Kelly, J., . . . Jones, A. M. (2013). Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance. Eur J Appl Physiol, 113(7), 1673-1684. doi:10.1007/s00421-013-2589-8

Wylie, L. J., Ortiz de Zevallos, J., Isidore, T., Nyman, L., Vanhatalo, A., Bailey, S. J., & Jones, A. M. (2016). Dose-dependent effects of dietary nitrate on the oxygen cost of moderate-intensity exercise: Acute vs. chronic supplementation. Nitric Oxide, 57, 30-39. doi:10.1016/j.niox.2016.04.004

Descargas

Publicado

2021-01-01

Cómo citar

Ramos Álvarez, J. J., Montoya Miñano, J. J., Miguel Tobal, F., Jodrá Jiménez, P., & Domínguez, R. (2021). Efectos de la suplementación con zumo de remolacha sobre la respuesta neuromuscular: revisión sistemática (Effect of beet juice supplementation (BJ) on neuromuscular response: a systematic review). Retos, 39, 893–901. https://doi.org/10.47197/retos.v0i39.79650

Número

Sección

Revisiones teóricas sistemáticas y/o metaanálisis