Rapidly progressive dementia as the initial presentation of human immunodeficiency virus infection

Authors

  • S. Ballesta-Martínez Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.
  • J. Espinosa-Rueda Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.
  • L. Tarí-Ferrer Servicio de Medicina Interna. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.
  • M.J. Crusells-Canales Servicio de Enfermedades Infecciosas. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.
  • A. Lambea-Gil Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

DOI:

https://doi.org/10.23938/ASSN.1002

Keywords:

Human immunodeficiency virus, HIV, HIV dementia

Abstract

Dementia associated with human immunodeficiency virus (HIV) is currently a rare cause of rapidly progressive dementia. Its appearance is not only limited to the late phases of the disease, but can sometimes be the presenting symptom.

We present the case of a patient who debuted with anxious-depressive symptoms and rapid cognitive deterioration with early repercussions on his daily functionality. HIV was detected in the study, with a higher viral load in cerebrospinal fluid than in plasma. Despite a torpid course at the beginning, antiretroviral therapy brought about a progressive improvement in the cognitive sphere, consistent with the decrease in the viral load.

Although rare, HIV continues to be a cause of dementia that primary care and hospital care professionals should not forget. The relevance of its early diagnosis lies in its potentially reversible nature.

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Author Biographies

S. Ballesta-Martínez , Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

  1. Instituto de Investigación Sanitaria de Aragón. Zaragoza. España.

J. Espinosa-Rueda , Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

  1. Instituto de Investigación Sanitaria de Aragón. Zaragoza. España.
  2. Servicio de Medicina Interna. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

A. Lambea-Gil , Servicio de Neurología. Hospital Clínico Universitario Lozano Blesa. Zaragoza. España.

  1. Instituto de Investigación Sanitaria de Aragón. Zaragoza. España.

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Published

2022-08-16

How to Cite

Ballesta-Martínez, S., Espinosa-Rueda, J., Tarí-Ferrer, L., Crusells-Canales, M., & Lambea-Gil, A. (2022). Rapidly progressive dementia as the initial presentation of human immunodeficiency virus infection . Anales Del Sistema Sanitario De Navarra, 45(2), e1002. https://doi.org/10.23938/ASSN.1002

Issue

Section

Clinical notes