Unusual evolution of reactive arthritis after endovesical immunotherapy with BCG
DOI:
https://doi.org/10.23938/ASSN.0875Keywords:
Arthritis reactive., Bladder cancer., Bacille Calmette- Guerin., BCG., Total hip replacement.Abstract
Intravesical instillation of BCG (Bacille Calmette-Guerin) is a therapy prepared with weakened strains of Mycobacterium bovis and is an effective complementary treatment for high-risk (non-musculoinfiltrating or non-invasive) bladder cancer. Although its safety for clinical use is high, endovesical immunotherapy is not without complications. Arthralgia and arthritis are infrequent, but potentially severe, complications, the early diagnosis of which can allow adequate medical treatment and avoid chronification of the pathology.
This case shows the therapeutic management of hip osteoarthritis in a 59-year-old woman, a rare and serious complication, secondary to a rare pathology such as reactive arthritis due to BCG instillation.
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LAMM DL. Efficacy and safety of bacille Calmette-Guerin immunotherapy in superficial bladder cancer. Clin Infect Dis 2000; 31: S86-S90. https://doi.org/10.1086/314064
LAMM DL, VAN DER MEIJDEN ADPM, MORALES A et al. (1992) Incidence and treatment of Bacillus Calmette Guerin intravesical therapy in superficial bladder cancer. J Urol 147; 596-600. https://doi.org/10.1016/s0022-5347(17)37316-0
Tinazzi E, Ficarra V, Simeoni S, Artibani W, Lunardi. C. Reactive arthritis following BCG immunotherapy for urinary bladder carcinoma: a systematic review. Rheumatol Int 2006; 26: 481-488. https://doi.org/10.1007/s00296-005-0059-2
MORALES A, NICKEL JG. Immunotherapy of superficial bladder cancer with BCG. World J Urol 1976; 3: 209-214. https://doi.org/10.1007/bf00632180
GUALLAR-GARRIDO S, JULIÁN E. Bacillus Calmette-Guérin (BCG) therapy for bladder cancer: an update. Immunotargets Ther 2020; 9: 1-11. https://doi.org/10.2147/itt.s202006
LAMM DL, STODGILL VD, STODGILL BJ, CRISPEN RG. Complications of bacillus Calmette-Guerin immunotherapy in 1278 patients with bladder cancer. J Urol 1986; 135: 272-274. https://doi.org/10.1016/s0022-5347(17)45606-0
RAHEEM OA, KALUNIAN K. KELLOGG PARSONS J. Artritis aguda secundaria a bacilo de Calmette-Guérin intravesical en el cáncer de vejiga. Actas Urol Esp 2012; 36: 461-466. https://doi.org/10.1016/j.acuro.2012.02.006
PRESCOTT S, JAMES K, BUSUTTIL A, HARGREAVE TB, CHISHOLM GD, SMYTH JF. HLA-DR expression by high grade superficial bladder cancer treated with BCG. Br J Urol 1989; 63: 264-269. https://doi.org/10.1111/j.1464-410x.1989.tb05187.x
RODRÍGUEZ F, PALOU J, R. MARTÍNEZ, O. RODRÍGUEZ, A. ROSALES, HUGUET J, VILLAVICENCIO H. Esquema práctico del manejo de los efectos adversos asociados con la instilación de BCG. Arch. Esp. Urol 2008; 61: 591-596. https://doi.org/10.4321/s0004-06142008000500004
CARTER JD, HUDSON AP. Reactive arthritis: clinical aspects and medical management. Rheum Dis Clin North Am 2009; 35: 21-44. https://doi.org/10.1016/j.rdc.2009.03.010
NGUYEN MH, GIORDANI MM, THOMPSON GR. The double-edged sword - prosthetic joint infection following BCG treatment for bladder cancer: a case report. BMC Infect Dis 2019; 19: 331. https://doi.org/10.1186/s12879-019-3951-1
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