Dural metastasis as the first manifestation of prostate cancer
Keywords:
Cáncer de próstata. Metástasis durales. Metástasis intracraneales. Hematoma subdural. Metástasis leptomeníngeas.Abstract
Metastases of prostate cancer to intracranial meninges are rare and often confused with meningiomas or chronic subdural hematomas. These usually occur in patients with a known cancer diagnosis in advanced stages of the disease, and only in some rare cases do its manifestations precede the detection of the primary tumour. The clinical presentation is unspecific. However, due to the affinity of this tumour for the base of the skull, it must be included in the differential diagnosis of men over 70 years of age with cranial nerve palsy. The treatment of these lesions has not been standardized. Within the therapeutic options we find surgical resection, chemotherapy, radiotherapy or a combination of these measures, and yet survival is poor. We present the case of a 77 year old male patient whose initial symptoms of prostate cancer were caused by a metastatic lesion to the dura, confirmed by histopathology. We also review the epidemiological, clinical and imaging highlights of this condition.Downloads
References
1. GUEDES BD, ROCHA AJ, GAMA HP, SILVA CJ. Dural metastases from prostate carcinoma: A systematic review of the literature a propos of six patients. Eur J Radiol 2011; 80: 236-240.
https://doi.org/10.1016/j.ejrad.2010.06.007
2. TOMLIN JM, ALLEYNE CH. Transdural metastasis from adenocarcinoma of the prostate mimicking subdural hematoma: case report. Surg Neurol 2002; 58: 329-331.
https://doi.org/10.1016/S0090-3019(02)00835-2
3. CONE LA, KOOCHEK K, HENAGER HA, FAUSEL R, GADE-ANDAVOLU R, POTTS BE et al. Leptomeningeal carcinomatosis in a patient with metastatic prostate cancer: case report and literature review. Surg Neurol 2006; 65: 372-375.
https://doi.org/10.1016/j.surneu.2005.08.026
4. NAYAK L, ABREY LE, IWAMOTO FM. Intracranial dural metastases. Cancer 2009; 115: 1947-1953.
https://doi.org/10.1002/cncr.24203
5. CHENG YK, WANG TC, YANG JT, LEE MH, SU CH. Dural metastasis from prostatic adenocarcinoma mimicking chronic subdural hematoma. J Clin Neurosci 2009; 16: 1084-1086.
https://doi.org/10.1016/j.jocn.2008.08.008
6. TREMONT-LUKATS IW, BOBUSTUC G, LAGOS GK, LOLAS K, KYRITSIS AP, PUDUVALLI VK. Brain metastasis from prostate carcinoma the M.D. Anderson Cancer Center experience. Cancer 2003; 92: 363-368.
https://doi.org/10.1002/cncr.11522
7. SUTTON MA, WATKINS HL, GREEN LK, KADMON D. Intracranial metastases as the first manifestation of prostate cancer. Urology 1996; 48: 789-793.
https://doi.org/10.1016/S0090-4295(96)00238-5
8. LONG MA, HUSBAND JE. Features of unusual metastases from prostate cancer. Br J Radiol 1999; 72: 933-941.
https://doi.org/10.1259/bjr.72.862.10673942
9. IZUMI K, MIZOKAMI A, NARIMOTO K, SUGIMOTO K, KOH E, KUMANO T et al. Cranial nerve deficit caused by skull metastasis of prostate cancer: three Japanese castration-resistant prostate cancer cases. Int J Clin Oncol 2010; 15: 631-634.
https://doi.org/10.1007/s10147-010-0098-x
10. DORSI MJ, ZENONOSA G, HSUA W, HUANGA J. Dural prostate adenocarcinoma metastasis with subdural hematoma mimicking the appearance of an epidural hematoma. Clin Neurol Neurosurg 2010; 112: 501-504.
https://doi.org/10.1016/j.clineuro.2010.02.009
11. CONFAVREUX CB, COTTON F, TEBIB JG. Advanced MRI could help to differentiate meningeal carcinomatosis with mass effect from cerebral metastasis in prostate cancer. Bull Cancer 2006; 93: 31-35.
12. TAGLE P, VILLANUEVA P, TORREALBA G, HUETE I. Intracranial metastasis or meningioma? An uncommon clinical diagnostic dilemma. Surg Neurol 2002; 58: 241-245.
https://doi.org/10.1016/S0090-3019(02)00831-5
13. LYONS MK, DRAZKOWSKI JF, WONG WW, FITCH TR, NELSON KD. Metastatic prostate carcinoma mimicking meningioma: case report and review of the literature. Neurologist 2006; 12: 48-52.
https://doi.org/10.1097/01.nrl.0000186809.04283.17
14. LATH CO, KHANNA PC, GADEWAR S, PATKAR DP. Intracranial metastasis from prostatic adenocarcinoma simulating a meningioma. Australas Radiol 2005; 49: 497-500.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2012 Anales del Sistema Sanitario de Navarra
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
La revista Anales del Sistema Sanitario de Navarra es publicada por el Departamento de Salud del Gobierno de Navarra (España), quien conserva los derechos patrimoniales (copyright ) sobre el artículo publicado y favorece y permite la difusión del mismo bajo licencia Creative Commons Reconocimiento-CompartirIgual 4.0 Internacional (CC BY-SA 4.0). Esta licencia permite copiar, usar, difundir, transmitir y exponer públicamente el artículo, siempre que siempre que se cite la autoría y la publicación inicial en Anales del Sistema Sanitario de Navarra, y se distinga la existencia de esta licencia de uso.
