Ageing of the Population and Number of Acquired Primary Blood Diseases in one Area of the Autnomous Region of Aragón

Abstract

Background: Aging probably comprises one of the major factors contributing to the onset of acquired primary blood diseases (APBD’s), most of which are of a chronic type. The purpose of this study is that to analyze the rate of occurrence (RO) of HPA in a population of 522,621 inhabitants (Males: 252,721; Females: 269,900) showing a negative vegetative growth (-1.4/ 105 inhabitants/year), said occurrence being dealt with separately for the population under age 60 and the population over age 60. Methods: In January-December, 1994, a estimate was made of the HPA rate of occurrence and rate of analyses among the patients from the area in question, dealing separately with those under age 60 and over age 60. The diagnostic criteria applied were Monoclonal Gammopathies of Undetermined Significance (MGUS’s) in keeping with Kyle’s criteria. Multiple Myeloma (MM) and Chronic Lymphatic Leukemia (CLL) in keeping with the Myeloma Task Force criteria, Non-Hodgkin’s Lymphoma (NHL) and Hodgkin’s Disease (HD) in keeping with the REAL classification, Myelodisplasic Syndromes (MS’s) and Acute Leukemia (AL) in keeping with the FAB classification, Chronic Myeloproliferative Syndromes (CMS’s) in keeping with the PVSG. For calculating the rates of occurrence, descriptive epidemiological methods were used. Results: The highest rates..